Type 1 Diabetes Clinical Trials

Type 1 Diabetes studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect type 1 diabetes clinical trial.

Filter Clinical TrialsFilter Clinical Trials

LOCATION

Anywhere

FILTER TRIALS

This study will be conducted in participants with type 1 diabetes mellitus on continuous subcutaneous insulin infusion (CSII) or pump therapy to evaluate the effect of LY900014 (Lyumjev) on blood sugar levels during exercise using different approaches on basal rate reduction and following …

This study compares insulin icodec (a new insulin) to insulin degludec (an insulin already available on the market) in people with type 1 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin degludec taken daily. Participants will…

This study is evaluating whether a drug may help individuals with type 1 diabetes mellitus.

This study is evaluating whether a drug may help prevent type 1 diabetes.

This study is evaluating whether a combination of insulin and pramlintide can improve glucose control in people with type 1 diabetes.

PiCASO Intervention Group

This study is evaluating whether a peer support coaching intervention may help improve self-management for adolescents and young adults with childhood onset chronic conditions.

Allogenic Human Islet Cells

This clinical study will evaluate the safety and effectiveness of Gastrin treatment with islet transplantation to help patients with difficult to control type 1 diabetes make insulin again and improve blood sugar control. This study involves two investigational (experimental) products not…

This study is evaluating whether metformin may help prevent hypertensive disorders of pregnancy in women with type 1 diabetes.

Diabetes has recently been referred to as "the epidemic of the 21st century". The reason why women with type 1 diabetes have a 2-3 fold greater risk of cardiovascular disease (CVD) compared to men with type 1 diabetes is unknown.The purpose of this study is to investigate whether or not es…

Experimental hypoglycemia

This study is evaluating whether a brain scan can help identify the mechanisms behind impaired awareness of hypoglycemia.

This is an open-label, multicenter, Phase 1 study evaluating the safety and tolerability of VCTX210A combination product in patients with T1D

Allogeneic adipose-derived mesenchymal stem cells (MSC)-Single Infusion

This study is evaluating whether a type of white blood cell called mesenchymal stem cells may help treat chronic kidney disease.

Insulin-alone closed-loop

This study is evaluating whether a new insulin dosing algorithm is safe for children with type 1 diabetes.

Home-based video visits

This study is evaluating whether a video visit can improve glycemic control for children with type 1 diabetes.

Mobile App + Basal-Bolus Optimization Algorithm

The Artificial Pancreas lab at McGill University has developed an optimization algorithm for adults with Type 1 Diabetes (T1D) on Multiple Daily Injection (MDI) therapy with the adjunctive use of glucose sensor technology, collectively known as sensor-augmented MDI therapy. The algorithm i…

This study is evaluating whether a new treatment for type 1 diabetes can help preserve insulin production.

This study is evaluating whether intranasal naloxone may help preserve the counterregulatory response to hypoglycemia in individuals with type 1 diabetes.

Intraportal infusion of islet cells

This study is evaluating whether islet cells from deceased donors may help treat type 1 diabetes.

Continuous Glucose Monitoring System

A Prospective, Multicenter Evaluation of Accuracy and Safety of the Eversense CGM System with Enhanced Features. The purpose of this clinical investigation is to evaluate the accuracy of the Eversense 524 Continuous Glucose Monitoring System (Eversense 524 CGM System) with next generation …

Sensor-Augmented Pump therapy

This study is evaluating whether a continuous glucose monitor may help improve blood sugar control for individuals with type 1 diabetes.

Study Medication (MBX-2982)

This study is evaluating whether a specific medication may help people with type 1 diabetes respond better to low blood sugar.

This study is evaluating whether a low carbohydrate diet may help improve insulin sensitivity and blood vessel health.

This study is evaluating whether a new drug can help people with type 1 diabetes.

This study is evaluating whether a combination of therapies may help improve insulin secretion and immune function for individuals with type 1 diabetes.

Intraportal infusion of islet cells

This study is evaluating whether islet cells from cadaver donors may help treat diabetes.

Intraportal infusion of islet cells

This study is evaluating whether transplanting human islet cells can be used to control blood sugar in people with type 1 diabetes.

Phase 1 randomized, double-blind, three period, crossover study comparing the pharmacodynamic, pharmacokinetic, safety and tolerability profiles for Arecor ultra-rapid insulin aspart (AT247), NovoLog® and Fiasp® in participants with type 1 diabetes mellitus (T1DM) during continuous subcuta…

This is a study assessing the feasibility of using the insulin-only configuration of the iLet bionic pancreas with initiation in pump-naïve people with type 1 diabetes in a primary care practice with either in-person training and follow-up (PC-IP) or with training and follow-up via telehea…

Virtual Diabetes Wellness Classes and Medically Tailored Meals

This study is evaluating whether a culturally tailored intervention can help people with diabetes.

This study is evaluating whether a new device can measure blood glucose levels without taking blood samples.

Virtual Educational Program

In this pilot study, study investigators aim to evaluate the acceptability and feasibility of a 3-month interactive virtual educational program, designed on principles of self-efficacy, reviewing aspects of Diabetes Mellitus care in adolescents and young adults with Type 1 Diabetes Mellitu…

Mindfulness Based Stress Reduction

This study is evaluating whether an online mindfulness program may help improve glucose control in adults with uncontrolled type 1 or type 2 diabetes.

Online Learning Modules

This study is evaluating whether behavioral family therapy can improve the health of children with type one diabetes mellitus.

Allogenic Islet Cell Transplantation

The primary objective of this study is to demonstrate the safety of allogenic islet transplantation in type 1 diabetic patients performed at the University of Virginia. The purpose is to demonstrate that islet transplantation can be performed safely and reliably achieves better glycemic c…

Bacillus Calmette-Guérin

The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect on pediatric Type 1 diabetes.

This study is evaluating whether Afrezza is safe and effective in combination with a basal insulin in pediatric subjects with type 1 or type 2 diabetes mellitus.

This study is evaluating whether a drug may help improve kidney function in adolescents with type 1 diabetes.

Motivational Enhancement System (MES)

This study is evaluating whether a multi-component behavioral intervention can help improve metabolic control among older adolescents and emerging adults with type 1 diabetes.

Mesenchymal Stem Cells (MSCs)

This study is evaluating whether a new treatment for type 1 diabetes may be effective.

Resilient, Empowered, Active Living-Telehealth (REAL-T)

This study is evaluating whether a lifestyle-based telehealth intervention can help improve glycemic control and psychosocial outcomes for individuals with type 2 diabetes.

Autologous adipose-derived mesenchymal stem/stromal cells (MSC) Higher Dose

This study is evaluating whether stem cells from fat may help treat kidney disease.

This study is evaluating whether group education visits can improve diabetes care for adolescents with type 1 diabetes.

This study is evaluating whether a drug that stimulates the release of a neurotransmitter called substance P can improve blood sugar control in people with type 1 diabetes.

Islet transplantation into the gastrointestinal submucosa

This study is evaluating whether islet transplantation is safe and effective for treating type I diabetes in people who have received a kidney transplant.

Automated Insulin Delivery Settings Initialization and Adaptation Algorithm

Obtain preliminary safety and performance data on a settings initialization and adaptation algorithm used in conjunction with closed-loop control.

This study is evaluating whether a drug can protect the kidneys from damage in people with type 1 diabetes.

This study is evaluating whether a drug called empagliflozin can improve blood sugar control and reduce cardiovascular risk in adolescents with type 1 diabetes.

Financial incentive (loss)

This study is evaluating whether financial incentives can help motivate adolescents with type 1 diabetes to improve their self-care.

Automated Insulin Delivery

This study is evaluating whether an artificial pancreas may help pregnant women with type 1 diabetes.

Experimental hyperglycemia

This study is evaluating whether a brain scan can help identify the mechanisms behind impaired awareness of hypoglycemia.

SUPPORT online platform for people with type 1 diabetes

This study is evaluating whether a web-based training and support program can reduce the frequency of hypoglycemia in people with type 1 diabetes.

Plan, Reflect, and Engage with Providers for Diabetes Care

Washington, United States

< 65

All Sexes

High Risk

Washington, United States

< 65

All Sexes

This study is evaluating whether a set of activities can improve diabetes self-care skills in adolescents and young adults with type 1 diabetes.

This study is evaluating whether a diabetes management platform (DMP) can help improve diabetes management for older patients with type 1 diabetes.

Sensor augmented MDI therapy plus mobile application

This study is evaluating whether a mobile application can help people with type 1 diabetes manage their insulin and exercise better.

Glucagon Nasal Powder [Baqsimi]

This study is evaluating the safety and tolerability of a study drug called nasal glucagon in pediatric participants with type 1 diabetes.

14-day outpatient intervention

A closed-loop insulin system, also referred to as the "artificial pancreas" (AP), is made up of an insulin pump, a continuous glucose monitor, and an application communicating between the two to adjust insulin administration based on glucose control. This is meant for the treatment of type…

Lactiplantibacillus plantarum

This study is evaluating whether a probiotic may help reduce inflammation and improve insulin production in individuals with type 1 diabetes.

Very Low Carbohydrate Diet

This study is evaluating whether a very low carbohydrate diet may help improve blood sugar levels in youth with type 1 diabetes.

This study is evaluating whether a drug that blocks immune cells can help prevent the loss of insulin-producing cells in people with type 1 diabetes.

VC-02 Combination Product

This study is evaluating whether a cell replacement therapy may help treat Type 1 Diabetes.

This study is evaluating whether islet cell transplantation can reverse diabetes in people with type 1 diabetes.

Primary objective: To determine whether oral ladarixin versus placebo adjunctive therapy improves glycemic control in overweight, insulin resistant (IR) adult subjects with type 1 diabetes (T1D). Secondary objectives: To ascertain the effect of ladarixin on glycemic variability as per CGM…

Diabetes behavior change skills training

This project is comprised of a two-arm randomized control trial (RCT) testing the feasibility, acceptability, and preliminary efficacy of a nationally scalable program, Activate, a 12-week, technology-delivered diabetes behavior-change skills training and physical activity promotion progra…

Regular physical activity has substantial health benefits in people with type 1 diabetes. The fear of hypoglycemia, both during and after exercise, is a major barrier to exercise in this population. A major obstacle to providing specific physical activity and exercise advice is that there …

Tolerogenic Dendritic Cell Vaccine

This study is evaluating whether a vaccine may help treat type 1 diabetes.

Insul-In This Together

This study is evaluating whether a family intervention can help improve diabetes management for teens with type 1 diabetes.

This study is evaluating whether a peer support intervention can improve glycemic control and other outcomes in young adults with type 1 diabetes.

Stem Cell Educator therapy

This study is evaluating whether a new treatment for type 1 diabetes may be effective.

Communication & Coping Intervention

Mothers of adolescents with type 1 diabetes experience high levels of depressive symptoms, which impair their ability to monitor and manage diabetes treatment effectively. Further, maternal depressive symptoms are one of the strongest predictors of negative outcomes in adolescents, includi…

This study is evaluating whether an internet-based cognitive behavioral therapy intervention can help improve depressive symptoms in adolescents with type 1 diabetes.

summerlunch+ At Home Food Skills Program

Food forms an integral part of diabetes management. As children mature into young adults, they must learn to adopt lifestyle behaviours critical for optimal diabetes care. The development of food preparation and cooking skills at a young age may help to facilitate healthy food choices in c…

Pneumovax 23- pneumococcal polysaccharide

This study is evaluating whether children with type 1 diabetes have adequate immune response to a common vaccine.

Positive Affect + Education

Washington, United States

< 18

All Sexes

Recruiting

Washington, United States

< 18

All Sexes

This study is evaluating whether a positive psychology intervention may help adolescents with type 1 diabetes.

Tablet based interactive diabetes education modules

This study is evaluating whether a tablet computer can help improve diabetes education for children with type 1 diabetes.

Immunosuppressive Agents

City of Hope National Medical Center, located in Duarte, CA, is hosting a clinical study on islet cell transplantation, an experimental procedure being evaluated as a treatment for patients with type 1 diabetes. Islet cell transplantation involves taking insulin-producing cells from organ …

Intradermal injection

The investigators are doing this research study to find out if the type of needle used to administer them affects the speed with which insulin and glucagon get into the blood. The investigators will compare a traditional insulin needle to an injection device, called the MicronJet, that use…

The Investigator is in the final phase of this study and is searching for a Hypo-AWARE Type 1 diabetic control group (Group 2). The primary goal for Group 2 in this study; is to demonstrate how hormones of Type 1 diabetics should react during hypoglycemic and non-hypoglycemic events. Enro…

Virtual home intervention

A virtual group of teens with type 1 diabetes, led by young adults with type 1 diabetes, will play active videogames and discuss activity and health. This study will evaluate the program for feasibility and user satisfaction.

This study is evaluating whether a 12 month treatment with ladarixin is effective to improve glycemic control in newly diagnosed T1D adult patients with preserved beta-cell function.

Dexcom G6 Continuous Glucose Monitor

This study is evaluating whether a continuous glucose monitor may help improve glucose control in children with type 1 diabetes.

This study is evaluating whether a specific method of delivering insulin during labor may help reduce the risk of complications for the baby.

This study is evaluating whether a camp for children with type 1 diabetes mellitus is effective.

Co-transplantation of PTG with pancreatic islets

This study is evaluating whether a combination of pancreatic islets and a kidney or liver transplant may help individuals with type 1 diabetes.

Promoting Resilience in Stress Management (PRISM)

This study is evaluating whether a novel intervention may help improve outcomes for adolescents with type 1 diabetes.

Community Health Worker added to diabetes team

This study is evaluating whether a community health worker can improve diabetes control in children with type 1 diabetes.

Follicular Phase Aerobic Exercise

Female participants with type 1 diabetes using oral contraceptives will be asked to wear a continuous glucose monitor for at least three days on two separate occasions (once during the last week of active pills and once during the no pill/placebo pill phase of the menstrual cycle). An exer…

Tandem t:slim X2 insulin pump with Control IQ technology

This study is evaluating whether a new pump can improve blood glucose control in pregnant women with type 1 diabetes.

This study is evaluating whether a drug may help preserve beta-cell function and delay the progression of type 1 diabetes.

This study is evaluating whether a sleep intervention may help improve sleep quality and blood glucose control for adults with type 1 diabetes.

Low-calorie sweetener restriction

Washington, United States

< 18

All Sexes

Recruiting

Washington, United States

< 18

All Sexes

This study is evaluating whether low-calorie sweeteners may help prevent diabetes complications among children with Type 1 Diabetes.

Very low carbohydrate diet