Reviewed by Michael Gill, B. Sc.
25 Type 1 Diabetes Clinical Trials Near Me
Top Hospitals for Type 1 Diabetes Clinical Trials
Image of University of Minnesota in Minnesota.
University of Minnesota
Minneapolis
7Active Trials
46All Time Trials for Type 1 Diabetes
1983First Type 1 Diabetes Trial
Top Cities for Type 1 Diabetes Clinical Trials
Type 1 Diabetes Clinical Trials by Phase of Trial
Phase < 1 Type 1 Diabetes Clinical Trials
4Active Type 1 Diabetes Clinical Trials
4Number of Unique Treatments
3Number of Active Locations
ResveratrolTrial 1-SSRICREONGlucagon-like peptide-1
Type 1 Diabetes Clinical Trials by Age Group
< 18 Type 1 Diabetes Clinical Trials
20Active Type 1 Diabetes Clinical Trials
Group education sessions for parents plus usual diabetes careAfrezzaBacillus Calmette-GuérinOnline Learning ModulesActive arm"MyPlan" - Individualized Structured Eating PlanteplizumabMind-body skills + diabetes education
Top Treatments for Type 1 Diabetes Clinical Trials
Treatment Name
Active Type 1 Diabetes Clinical Trials
All Time Trials for Type 1 Diabetes
First Recorded Type 1 Diabetes Trial
Intraportal infusion of islet cells
3
4
2003
Bacillus Calmette-Guérin
2
2
2015
teplizumab
2
2
2019
Metformin
2
16
2003
t:slim X2 insulin pump with Control-IQ technology 1.5
2
2
2022
Recently Completed Studies with FDA Approved Treatments for Type 1 Diabetes
Treatment
Year
Sponsor
YG1699
2021
Youngene Therapeutics Inc., Ltd.

What Are Type 1 Diabetes Clinical Trials?

Type 1 Diabetes is a chronic and potentially life-threatening condition wherein a patient's pancreas no longer produces insulin or produces very little. Insulin is used throughout the body to control boog glucose levels, which may cause further medical complications if not kept within a specific range.

When the pancreas no longer produces insulin, patients with Type 1 Diabetes need to regulate their blood sugar levels through various medications and insulin injections. This condition typically affects children, teens, and young adults and is commonly referred to as Juvenile Diabetes. There are currently more than 280,000 adolescents living with this condition in the United States.

Trials for Type 1 Diabetes are an essential cornerstone to understanding and managing this chronic condition. The research and tests undertaken by medical professionals hope to uncover new ways of treating, preventing, and managing the condition. The secondary aim of the trials is to give existing patients a better quality of life and find a cure. There is currently no available cure for Type 1 Diabetes.

Why Is Type 1 Diabetes Being Studied Through Clinical Trials?

Type 1 Diabetes is a debilitating condition that can affect multiple facets of a patient's life. Without proper management, patients can develop severe co-morbidities. In some cases, Type 1 Diabetes has also been linked to multiple deaths.

For this reason, researchers are studying the condition to improve symptom management, prevent the onset of co-morbidities, study the impact of new medications, and test the effectiveness of medical equipment.

Typically, trials are done to test new medications to help existing patients or to prevent the diagnoses of others using preventative drugs.

What Are The Types of Treatments Available For Type 1 Diabetes?

Diabetes is treated with a series of medications, with the primary medication being insulin. New forms of insulin delivery are being tested in Type 1 trials, as well as the accompanying delivery systems such as insulin pumps.

Trials also consist of behavioral therapies, diagnostics, and uncovering new risk factors that may help medical professionals diagnose or pinpoint Type 1 before it is irreversible. There is no current cure for diabetes, meaning researchers are focusing on ways to prevent future diagnoses and reverse the effects on existing patients.

There is also no specific cause for Type 1 Diabetes, and researchers are currently working on narrowing their search for any genetic significance that may help with diagnostic testing.

What Are Some Recent Breakthrough Clinical Trials For Type 1 Diabetes?

With research and understanding about Type 1 Diabetes growing exponentially in recent years, multiple new research findings have surfaced. The most noteworthy findings include the following:

2020: Type 1 Diabetes Screening – A study in Germany found that screening young children between the age of two and five years old reduced the risk of undiagnosed diabetic juveniles developing diabetic ketoacidosis. This serious condition affects people with diabetes with mismanaged blood sugar or undiagnosed diabetes. It can be life-threatening for Type 1 diabetics, particularly children.

2022: Pancreatic Cell Regeneration – Researchers in Melbourne, Australia, at Monash University successfully rehabilitate previously inhibited insulin-producing pancreatic cells (also known as β-cells or beta-cells). This therapy has furthered the cause for a potential cure for Type 1 Diabetes and the hastened reversal of Type 2.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 2nd, 2021

Last Reviewed: October 17th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

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