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Constant Routine Protocol for High Blood Pressure

N/A
Waitlist Available
Research Sponsored by University of Alabama at Birmingham
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up expression of bmal1 and period 3 during a 30-hour constant routine protocol
Awards & highlights

Summary

This trial looks at how well central and peripheral circadian mechanisms work in Blacks with dipping and non-dipping systolic blood pressure.

Eligible Conditions
  • High Blood Pressure
  • Circadian Rhythm

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~expression of bmal1 and period 3 during a 30-hour constant routine protocol
This trial's timeline: 3 weeks for screening, Varies for treatment, and expression of bmal1 and period 3 during a 30-hour constant routine protocol for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Buccal cell mRNA expression
Core body temperature amplitude
Core body temperature phase
+2 more
Secondary outcome measures
Cortisol amplitude
Cortisol phase

Trial Design

1Treatment groups
Experimental Treatment
Group I: Constant Routine ProtocolExperimental Treatment1 Intervention
Participants will be kept in constant conditions for 30 hours to observe circadian physiology in the absence of light, physical activity, and meals.

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Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor
1,599 Previous Clinical Trials
2,287,888 Total Patients Enrolled
American Heart AssociationOTHER
336 Previous Clinical Trials
4,935,112 Total Patients Enrolled
~6 spots leftby Jul 2025
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