App based mindfulness program (ABMP) for Inflammation

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Inflammation+2 More
App based mindfulness program (ABMP) - Behavioral
Eligibility
18+
Female
What conditions do you have?
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Study Summary

This trial is investigating the effects of stress and glucose intake on the immune system at the molecular level, including gene expression and protein analysis of immune cells in real time.

Eligible Conditions
  • Inflammation
  • Lupus Erythematosus, Systemic

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Inflammation

Study Objectives

6 Primary · 6 Secondary · Reporting Duration: Baseline and 8 weeks

Baseline and 8 weeks
Change in Five Facet Mindfulness Questionnaire (FFMQ)
Change in PROMIS-Depression Score
Change in PROMIS-GH (Patient-Reported Outcomes Measurement Information System Global Health) score
Change in PROMIS-Positive Affect Score
Change in State Trait Anxiety Inventory (STAI) Score
Change in expression of 'immune cells activation markers'
Change in inflammatory cytokines level
Change in neutrophil function as assessed by Neutrophil extracellular trap(NET) formation
Change in neutrophil function as assessed by reactive oxygen species (ROS) production
Change in neutrophils' migratory ability as assessed by change in "distance travelled" by neutrophils
Change in neutrophils' migratory ability as assessed by change in neutrophils' velocity
Change in phagocytic index of neutrophils
Change in the Perceived Stress Scale
Change in the cytokine secretion level from immune cells
Change in the expression of stress-induced genes
Change in the gene expression pattern of stress induced genes
Change in the methylation pattern of stress-induced genes
Change in the monocyte activation level

Trial Safety

Safety Progress

1 of 3

Other trials for Inflammation

Trial Design

2 Treatment Groups

control
1 of 2
App based mindfulness program (ABMP)
1 of 2
Active Control
Experimental Treatment

40 Total Participants · 2 Treatment Groups

Primary Treatment: App based mindfulness program (ABMP) · No Placebo Group · Phase < 1

App based mindfulness program (ABMP)
Behavioral
Experimental Group · 1 Intervention: App based mindfulness program (ABMP) · Intervention Types: Behavioral
controlNoIntervention Group · 1 Intervention: control · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline and 8 weeks

Who is running the clinical trial?

University of Wisconsin, MadisonLead Sponsor
1,061 Previous Clinical Trials
2,563,759 Total Patients Enrolled
9 Trials studying Inflammation
797 Patients Enrolled for Inflammation
David Beebe, PhDPrincipal InvestigatorUW Madison

Eligibility Criteria

Age 18+ · Female Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
Lupus can be diagnosed using the ACR 1987 criteria or the SLICC 2012 criteria, or by a board-certified rheumatologist.
You have a body mass index (BMI) under 35.
The person must have access to an iOS or android smartphone in order to use the app on a daily basis.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 7th, 2021

Last Reviewed: October 4th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.