Pandas Clinical Trials
Here are the 6 most popular medical studies for pandas
Monoclonal Antibodies
Ocrelizumab for Schizoaffective Disorder
This trial is investigating whether some people diagnosed with schizophrenia or bipolar disorder may actually have a brain disease caused by auto-antibodies. These auto-antibodies attack brain receptors, leading to symptoms
Procedure
Stem Cell Transplant for Autoimmune Diseases
This trial is testing a new treatment strategy for children and young adults with autoimmune diseases that are unresponsive to conventional treatments. The new treatment involves delivering high doses of immunosuppressive therapy followed by an autologous stem cell transplant (ASCT). The goal is to purge the pathogenic, autoreactive immune system and reset the immune system.
Stem Cell Therapy
SSC Transplant + Testicular Tissue Grafting for Male Infertility
This trial will test whether it is safe and feasible to transplant spermatogonial stem cells in order to restore fertility for men who have had their testicular tissue frozen prior to gonadotoxic therapy.
Neurostimulation Device
VNS for Epilepsy
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
Stem Cell Transplant
Bone Marrow/Kidney Transplant for Blood Disorders & Chronic Kidney Disease
This trial is for a combined bone marrow and kidney transplant from a partially matched related donor to treat a blood disorder and kidney disease. The expectation is to have 10 people participate.
Popular filter options for pandas trials
Multiple Sclerosis Clinical Trials
View 20 Multiple Sclerosis medical studies.
Anti-bacterial
Oral Antibiotics for Prosthetic Joint Infections
This trial is testing whether a 7-day course of an oral, prophylactic antibiotic can reduce the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.
Thromboxane A2 Receptor Antagonist
Oral Ifetroban for Scleroderma
This trial will test ifetroban, a new drug, to see if it is safe and effective for treating scleroderma, a disease that causes the hardening and tightening of skin, or scleroderma-associated pulmonary arterial hypertension.
Vitamin
Vitamin D + Fish Oil for Health Improvement
This trial is studying whether taking daily dietary supplements of vitamin D3 or omega-3 fatty acids reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses.
Myasthenia Gravis Clinical Trials
View 16 Myasthenia Gravis medical studies.
Anti-bacterial
Oral Antibiotics for Prosthetic Joint Infections
This trial is testing whether a 7-day course of an oral, prophylactic antibiotic can reduce the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.
Thromboxane A2 Receptor Antagonist
Oral Ifetroban for Scleroderma
This trial will test ifetroban, a new drug, to see if it is safe and effective for treating scleroderma, a disease that causes the hardening and tightening of skin, or scleroderma-associated pulmonary arterial hypertension.
Vitamin
Vitamin D + Fish Oil for Health Improvement
This trial is studying whether taking daily dietary supplements of vitamin D3 or omega-3 fatty acids reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses.
Monoclonal Antibodies
Rituximab + Cyclosporine for Glomerulonephritis
This trial is testing the safety and effectiveness of combining two drugs to treat membranous nephropathy, a kidney disease associated with damage to the walls of the glomeruli. The first drug, rituximab, is an immunosuppressant that attempts to reduce the activity of the immune system. The second drug, cyclosporine, is a blood pressure lowering medication. The trial will last up to 2 years, and participants will have frequent blood and urine tests.
Pandas Clinical Trials With No Placebo
View 33 pandas medical studies that do not have a placebo group.
Anti-bacterial
Oral Antibiotics for Prosthetic Joint Infections
This trial is testing whether a 7-day course of an oral, prophylactic antibiotic can reduce the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.
Monoclonal Antibodies
Rituximab + Cyclosporine for Glomerulonephritis
This trial is testing the safety and effectiveness of combining two drugs to treat membranous nephropathy, a kidney disease associated with damage to the walls of the glomeruli. The first drug, rituximab, is an immunosuppressant that attempts to reduce the activity of the immune system. The second drug, cyclosporine, is a blood pressure lowering medication. The trial will last up to 2 years, and participants will have frequent blood and urine tests.
View More Pandas Trials
See another 11 medical studies focused on pandas.
Frequently Asked Questions
Introduction to pandas
What are the top hospitals conducting pandas research?
When it comes to pioneering clinical trials for pandas (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections), several top hospitals are leading the way. Massachusetts General Hospital in Boston is at the forefront of research, currently conducting three active panda trials. Similarly, the Hospital for Special Surgery in New york is making significant strides with three ongoing clinical studies focused on this condition. Yale University in New Haven and Cleveland Clinic in Cleveland both have two active panda trials underway, contributing to the growing body of knowledge surrounding this complex disorder. Mayo Clinic in Rochester also joins these esteemed institutions with two ongoing panda trials.
Pandas is a unique pediatric neuropsychiatric disorder that typically begins after a streptococcal infection, such as strep throat or scarlet fever. It involves sudden-onset obsessive-compulsive symptoms, motor tics, anxiety, and other behavioral changes that can be debilitating for affected children and their families. The lack of completed pandas trials thus far highlights both the complexity of the condition and the pressing need for further research.
By conducting these cutting-edge clinical trials, these hospitals are dedicated to unraveling the mysteries of pandas and developing more effective treatment options for affected children. Their efforts not only offer hope to families dealing with this challenging condition but also contribute significantly to medical advancements worldwide
Which are the best cities for pandas clinical trials?
When it comes to pandas clinical trials, several cities emerge as prominent hubs for research and development. Boston, Massachusetts leads the pack with 10 active trials exploring a range of treatments like Cohort B, Arm B2P: BNT162b2, Nivolumab, and Naproxen Sodium. New york City follows closely behind with 10 ongoing studies focusing on interventions such as Nivolumab and Cohort B. Saint Louis, Missouri also plays a significant role in pandas clinical trials with 8 active studies investigating treatments like Molgramostim and Peresolimab. Philadelphia, Pennsylvania contributes to the field with 6 trials studying various interventions including Oral Ifetroban. Lastly, Baltimore, Maryland conducts 5 active trials focusing on therapeutics like Nivolumab and Molgramostim. These cities serve as vital centers for pandas clinical research offering potential breakthroughs in care for patients seeking improved outcomes.
Which are the top treatments for pandas being explored in clinical trials?
In clinical trials, researchers are exploring various treatments for PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections). Some of the top treatments being investigated include:
- Intravenous Immunoglobulin (IVIG): Undergoing evaluation in multiple trials
- Antibiotics: Being tested to target and eradicate streptococcus infection
- Cognitive-behavioral therapy (CBT): Investigated as a means to alleviate symptoms and enhance coping strategies.
What are the most recent clinical trials for pandas?
Recent clinical trials offer hope for individuals with pandas, a neuropsychiatric disorder. One promising study explores the use of CD3/CD19 depletion in autologous stem cell transplants, aiming to enhance treatment outcomes. Another trial investigates the efficacy and safety of a 4 mg/kg dose cohort for pandas patients. In addition, researchers are evaluating the potential benefits of VCTX211 unit and J8-K4S2 therapies through phase 1 and phase 2 studies. Furthermore, peresolimab is being investigated in a phase 2 trial to assess its effectiveness against pandas symptoms. These ongoing trials represent significant advancements towards improving the lives of those affected by this condition.
What pandas clinical trials were recently completed?
I'm sorry, but I cannot provide an accurate answer to your question as there is no information about any recently completed clinical trials specifically focused on pandas. Pandas, or Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections, is a complex condition that primarily affects children. While research and studies are ongoing to better understand and treat this disorder, it appears that there haven't been any recent clinical trials directly addressing pandas.