Trials in Austin, Texas
Here are the top 10 medical studies for colorectal cancer in Austin, Texas
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Phase 3 Trials
Chemotherapy
Chemotherapy + Atezolizumab for Colon Cancer
Recruiting2 awardsPhase 3
Hot Springs, Arkansas
This trial is testing whether adding atezolizumab to standard chemotherapy works better than chemotherapy alone for patients with stage III colon cancer who have a specific genetic defect. The chemotherapy drugs aim to kill cancer cells, while atezolizumab helps the immune system attack the cancer. Researchers hope this combination will improve survival rates and quality of life for these patients.
Chemotherapy
Vitamin D3 + Chemotherapy + Bevacizumab for Colorectal Cancer
Recruiting2 awardsPhase 3
Hot Springs, Arkansas
This trial is testing if vitamin D3 along with regular cancer drugs and another drug that helps the immune system can better treat colorectal cancer that has spread. Vitamin D3 may help the body use essential minerals, making the cancer drugs more effective. Vitamin D3 has been shown to slow down cancer cell growth and help them mature, and it has been effective in reducing intestinal tumors in animal studies.
Chemotherapy
ctDNA Testing for Colon Cancer Treatment Prediction
Recruiting1 awardPhase 2 & 3
Hot Springs, Arkansas
This trial tests how well ctDNA testing in the blood predicts treatment for patients with stage IIA colon cancer after surgery. ctDNA are circulating tumor cells that are shed by tumors into the blood. Finding ctDNA in the blood means that there is very likely some small amounts of cancer that remain after surgery. However, this cancer, if detected, cannot be found on other tests usually used to find cancer, as it is too small. Testing for ctDNA levels may help identify patients with colon cancer after surgery who do benefit, and those who do not benefit, from receiving chemotherapy.
Small Molecule
MRTX849 + Cetuximab for Colorectal Cancer
Recruiting2 awardsPhase 3
Temple, Texas
This trial is testing a new treatment for patients with colorectal cancer. The treatment combines two drugs that work together to block cancer growth and prevent its spread. One of the drugs has shown promise in treating other types of cancer as well.
Trials With No Placebo
XL092 + Immunotherapy for Cancer
Recruiting1 awardPhase 1
San Antonio, Texas
This trial is testing a new drug called XL092 by itself and with two other drugs, atezolizumab and avelumab. It targets patients with advanced solid tumors who may not respond to current treatments. XL092 aims to stop cancer cells from growing, while atezolizumab and avelumab help the immune system fight the cancer. Atezolizumab is approved for various cancers, including breast and urothelial carcinoma, and has shown efficacy in combination with chemotherapy.
Checkpoint Inhibitor
Nivolumab + Trametinib (+/- Ipilimumab) for Colorectal Cancer
Recruiting1 awardPhase 1 & 2
Temple, Texas
This trial is testing a combination of drugs to treat patients with advanced colon or rectal cancer who have already tried other treatments. The drugs help the immune system fight cancer and block proteins that help cancer grow. One of the drugs being tested has shown promise in treating advanced colorectal cancer.
STAT3 Inhibitor
Oral STAT3 Inhibitor for Cancer
Recruiting1 awardPhase 1
San Antonio, Texas
This trial will test a new compound, TTI-101, which is a direct inhibitor of the protein STAT3. This protein is involved in the development and growth of many types of cancer, but there is no current drug that targets it. TTI-101 will be given orally to patients with various types of solid tumors, to determine if it is safe and effective in reducing the growth of these tumors.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.