This trial is testing a new drug, CBX-12, on people with cancer that has spread or returned after treatment. The goal is to see if it is safe and what side effects it has.
- Small Cell Lung Cancer
- Solid Tumors, Adult
- Ovarian Cancer
- Breast Cancer
- Colorectal Cancer
- Pancreatic Cancer
- Appendiceal Cancer
- Non-Small Cell Lung Cancer
- Stomach Cancer
- Esophageal Cancer
- Bladder Cancer
5 Primary · 10 Secondary · Reporting Duration: 15 months
5 Treatment Groups
Phase 1 Dose Escalation (Daily Dosing x 5)
1 of 5
Phase 1 Dose Escalation (Once Weekly Dosing )
1 of 5
Phase 2 Small Cell Lung Cancer Expansion Cohort
1 of 5
Phase 1 Dose Escalation (Daily Dosing x 3)
1 of 5
Phase 2 Ovarian Cancer Expansion Cohort
1 of 5
112 Total Participants · 5 Treatment Groups
Primary Treatment: CBX-12 · No Placebo Group · Phase 1 & 2
Who is running the clinical trial?
Age 18+ · All Participants · 4 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
How many participants has the study recruited thus far?
"Affirmative. According to clinicaltrials.gov, this research program is enrolling patients at 4 distinct locations and the study has been active since May 3rd 2021. 112 individuals are eagerly sought after by researchers involved in the trial." - Anonymous Online Contributor
Is the clinical trial for this study being administered widely across North America?
"Presently, this trial is being run in 4 different sites located in Austin, San Antonio and New Haven among other places. Participants should select the closest clinical centre to reduce travel inconveniences." - Anonymous Online Contributor
What is the primary purpose of this research endeavor?
"This trial will span 15 months and the primary outcome is to be evaluated by measuring overall response rate (ORR). The secondary outcomes are Area under the Curve from 0-24 hours of CBX-12, Clearance (CL) of CBX-12, and Maximum concentration of CBX-12 as defined through PK Analysis." - Anonymous Online Contributor
Are there opportunities to join the research team of this experiment?
"Affirmative, the information found on clinicaltrials.gov suggests that this investigation is presently enrolling participants. This clinical trial was initially uploaded on May 3rd 2021 and recently modified on May 9th 2022. The research requires 112 individuals from 4 various sites to take part in it." - Anonymous Online Contributor