5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy for Rectal Adenocarcinoma

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Duluth Clinic Ashland, Ashland, WIRectal Adenocarcinoma+1 More5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy - Procedure
Eligibility
50 - 70
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether colonoscopies every 10 years are as effective as every 5 years in preventing colorectal cancer.

Eligible Conditions
  • Adenomatous Polyps
  • Rectal Adenocarcinoma
  • Colorectal Cancer

Treatment Effectiveness

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 10 years

10 years
Colorectal cancer mortality
Incidence of advanced adenoma
Incidence of colorectal cancer
Incidence of stage III-IV colorectal cancer

Trial Safety

Trial Design

2 Treatment Groups

Arm 2
1 of 2
Arm 1
1 of 2

Experimental Treatment

9500 Total Participants · 2 Treatment Groups

Primary Treatment: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy · No Placebo Group · N/A

Arm 2
Procedure
Experimental Group · 1 Intervention: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy · Intervention Types: Procedure
Arm 1
Procedure
Experimental Group · 1 Intervention: 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 10 years

Who is running the clinical trial?

NRG OncologyLead Sponsor
221 Previous Clinical Trials
86,360 Total Patients Enrolled
1 Trials studying Rectal Adenocarcinoma
362 Patients Enrolled for Rectal Adenocarcinoma
National Cancer Institute (NCI)NIH
13,156 Previous Clinical Trials
41,154,100 Total Patients Enrolled
16 Trials studying Rectal Adenocarcinoma
1,152 Patients Enrolled for Rectal Adenocarcinoma
Robert Schoen, MDStudy ChairUniversity of Pittsburgh
1 Previous Clinical Trials
137 Total Patients Enrolled

Eligibility Criteria

Age 50 - 70 · All Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Frequently Asked Questions

Who can be considered a viable candidate for this trial?

"This study is currently searching for 95 hundred individuals, aged 50 to 70 years old, who possess adenocarcinoma. To meet the inclusion criteria, participants must have a first-time diagnosis of 1 or 2 non-advanced tubular adenomas within 4 years prior to randomization; sessile serrated polyps/adenomas (provided they do not fit advanced adenoma standards); undergone an extensive and thorough colonoscopy that reached their cecum with sufficient cleansing in the same time frame; underwent complete excision of all seen polyps from the qualifying colonoscopy; can read and understand English or" - Anonymous Online Contributor

Unverified Answer

Are there current openings for enrollment in this research?

"According to the listing on clinicaltrials.gov, this research project is still in its recruitment phase. The first posting was made on October 6th 2021 with subsequent changes noted as recent as March 30th 2022." - Anonymous Online Contributor

Unverified Answer

How many medical centers are operating this research project?

"At present, this clinical trial is operating in 100 cities across the nation. These include Arroyo Grande, Saint Paul and Sandstone as well as other locales. Patients are advised to consider enrolling at a site nearest them to avoid extensive travel requirements." - Anonymous Online Contributor

Unverified Answer

Does this research project accept individuals younger than 85 years of age?

"This clinical trial is recruiting patients aged between 50 and 70 years old. There are 7 trials for minors, as well as 773 studies for seniors over the age of 65." - Anonymous Online Contributor

Unverified Answer

How many individuals are receiving treatment as part of the current clinical trial?

"To complete this trial, 9500 eligible patients are necessary. In particular, individuals can join the medical study at Mission Hope Medical Oncology - Arroyo Grande in California or Regions Hospital of Minnesota." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.