← Back to Search

Medication Reduction for Aging

Phase 4

Waitlist Available

Led By Scott Garrison, MD, PhD

Research Sponsored by University of Alberta

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

≥80 years of age

Using ≥6 long-term oral medications (defined as orally administered medications dispensed ≥2 times in the preceding 200 days)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an expected average of 2 years

Awards & highlights

Study Summary

This trial is designed to study whether reducing the number of medications that older adults take will improve their health outcomes.

Who is the study for?

This trial is for individuals who are 80 years or older, take six or more long-term oral medications, see participating primary care providers regularly, and live independently (not in a nursing home). There are no specific exclusion criteria.Check my eligibility

What is being tested?

The study tests if reducing medication doses can benefit seniors. It involves reviewing patients' current medications to find the lowest effective doses for symptom relief and adjusting drugs that control blood pressure and sugar to safer levels.See study design

What are the potential side effects?

Since the intervention involves lowering medication dosages already prescribed, side effects may include changes in how well symptoms are managed. However, this approach aims to reduce adverse drug reactions common in older adults.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 80 years old or older.

Select...

I am taking 6 or more long-term oral medications.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an expected average of 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an expected average of 2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an expected average of 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Composite of all-cause mortality or nursing home admission

Secondary outcome measures

Acute care costs

All-cause mortality

All-cause unplanned hospitalization or emergency room visit

+13 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Medication minimizationExperimental Treatment1 Intervention

Patients have a dedicated medication minimization visit with their usual primary care provider to which they bring all of their medications (a so-called "brown bag" medication review).

Group II: Usual CareActive Control1 Intervention

Patients will continue to receive care as appropriate but no dedicated visit to review and minimize medications will be organized as a result of the study. Medications are free to be minimized during the normal course of care should the need arise.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of AlbertaLead Sponsor

886 Previous Clinical Trials

382,978 Total Patients Enrolled

3 Trials studying Frailty

591 Patients Enrolled for Frailty

Scott Garrison, MD, PhDPrincipal InvestigatorUniversity of Alberta

Media Library

Medication minimization Clinical Trial Eligibility Overview. Trial Name: NCT05307666 — Phase 4

Frailty Research Study Groups: Usual Care, Medication minimization

Frailty Clinical Trial 2023: Medication minimization Highlights & Side Effects. Trial Name: NCT05307666 — Phase 4

Medication minimization 2023 Treatment Timeline for Medical Study. Trial Name: NCT05307666 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has the FDA sanctioned medication reduction as a viable medical approach?

"Given the fact that this medication is approved, our team at Power has assigned a score of 3 to signify its safety."

Answered by AI

Are there still openings available for patients to take part in this trial?

"Data from clinicaltrials.gov indicates that enrollment in this trial has closed as of August 2nd 2022. Although, there are 380 alternative trials with open recruitment processes available to interested participants at present."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

MinMed: Do Older Adults do Better With Less Medication

Scott Garrison 2022. "MinMed: Do Older Adults do Better With Less Medication". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05307666.