Educational Brochure for Overmedication

Overseen By Patricia Kim

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Icahn School of Medicine at Mount Sinai

Must be taking: PPIs, Benzodiazepines, Z-drugs, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 5

50 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

By 2030, the majority of World Trade Center (WTC) rescue and recovery workers (responders) will be aged 65 and over and at risk for aging-related conditions and consequences including the concurrent use of five or more medications (i.e., polypharmacy). The purpose of this research study is to investigate an educational approach targeting polypharmacy through de-prescribing unnecessary and burdensome medications via the support of informed discussions between WTC responders and their prescribing physicians.

Who Is on the Research Team?

Fred Ko, MD

Principal Investigator

Icahn School of Medicine at Mount Sinai

Are You a Good Fit for This Trial?

This trial is for World Trade Center responders who are aging and may be taking five or more medications, putting them at risk of overmedication. The study aims to help these individuals reduce unnecessary medication through education.

Inclusion Criteria

A WTC responder already enrolled in the 'Promoting Healthy Aging Among WTC Responders: Frailty Trajectories and Intervention Strategies' study cohort

I am 50 years old or older.

I am currently taking medication from one of the specified classes (PPIs, BZs, Z-drugs, FGAs, or SMRs).

Exclusion Criteria

Not applicable.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline Assessment

Participants complete baseline surveys about beliefs and attitudes regarding medications and de-prescribing

1 week

1 visit (in-person)

Intervention

Participants review educational brochures and discuss deprescribing options with their prescriber

4 weeks

2 visits (in-person)

Follow-up

Participants are monitored for changes in medication management and attitudes towards deprescribing

6 months

2 visits (virtual)

What Are the Treatments Tested in This Trial?

Interventions

• Educational brochure for deprescribing

Trial Overview The intervention being tested is an educational brochure designed to guide WTC responders on deprescribing, encouraging informed conversations with their doctors about managing multiple medications.

How Is the Trial Designed?

Group I: World Trade Center (WTC) Responders Experimental Treatment 1 Intervention

World Trade Center (WTC) rescue and recovery workers (responders).

Who Is Running the Clinical Trial?

Icahn School of Medicine at Mount Sinai

Lead Sponsor

Trials

933

Recruited

579,000+