← Back to Search

Behavioural Intervention

ePACE Experimental Condition for Substance Abuse (ASPIRE Trial)

N/A

Recruiting

Research Sponsored by Oregon Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

ASPIRE Trial Summary

"This trial aims to compare two different web-based intervention programs, ePACE and eFACE, for adolescents with substance use and common behavioral problems. The goal is to see if these interventions are more effective than

Who is the study for?

This trial is for adolescents with mild to moderate substance use and related behavioral health issues. They should be willing to engage in web-based interventions and complete assessments over a 6-month period. Specific eligibility details are not provided, but typically participants must meet certain age and health criteria.Check my eligibility

What is being tested?

The study compares two web-based interventions: ePACE, which is personalized, allowing youth choice in content and engagement level; versus eFACE, a fixed intervention without personalization. Both aim to address drug abuse, interpersonal relations, negative emotions, and stress.See study design

What are the potential side effects?

Since the interventions are non-medical (web-based counseling modules), traditional side effects like those seen with medications are not expected. However, discussing sensitive topics may cause discomfort or emotional distress.

ASPIRE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Adolescent Substance Use from baseline to 3 months

Adolescent Substance Use from baseline to 6 months

Parent Report Externalizing Problems from baseline to 3-months

+7 more

Secondary outcome measures

Child Global Assessment Scale (CGAS) from baseline to 3-months

Child Global Assessment Scale (CGAS) from baseline to 6-months

Peer Encouragement and Influence from baseline to 3 months

+3 more

Other outcome measures

Change in Urine assay - 3 months to 6 months

Change in Urine assay - baseline to 3 months

Emotion Regulation - baseline to 6 months

+1 more

ASPIRE Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: ePACE Experimental ConditionExperimental Treatment1 Intervention

The experimental intervention to be administered, ePACE, is a web-based brief intervention that includes personalization and youth-centered features. Feedback is provided based on youth's responses to activities, exercises, and quizzes to guide each individual's behavior change efforts.

Group II: eFACE Active Comparator ConditionActive Control1 Intervention

The eFACE active comparator arm involves the eFACE intervention and includes content that is similar to the ePACE experimental intervention, but modules are offered in a fixed order with no tailoring features. No personalized feedback based on youth responses are provided to inform individual youth's behavior change efforts.

Group III: Waiting List Comparison GroupActive Control1 Intervention

Youth in the waitlist comparison (WC) condition will not have access to the ePACE or eFACE modules until the final (6-month) assessment has been completed. Thus, the WC group will serve as a "no intervention" comparison group.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Oregon Research InstituteLead Sponsor

84 Previous Clinical Trials

66,147 Total Patients Enrolled

5 Trials studying Substance Abuse

14,536 Patients Enrolled for Substance Abuse

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current number of participants enrolled in this research study?

"Indeed, data on clinicaltrials.gov confirms the ongoing recruitment efforts for this research project. The trial was first listed on December 1st, 2023 and most recently revised on March 5th, 2024. Enrollment is targeted at securing 120 participants from a single site."

Answered by AI

May I inquire about the criteria for potential participation in this medical study?

"To qualify for this study, candidates must be adolescents aged between 12 and 17 years with a history of substance misuse. The trial aims to enroll 120 participants in total."

Answered by AI

Are potential participants currently able to apply for enrollment in this study?

"Affirmative, information from clinicaltrials.gov indicates that this investigation is currently enrolling subjects. Originally shared on 12/1/2023 and last revised on 3/5/2024, the research aims to recruit 120 individuals at a single site."

Answered by AI