Pre-Exposure Prophylaxis for HIV Prevention
(MAPS PrEP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
For this study the investigators aim to see if giving participants an oral HIV prevention medication on a medical van, is a good option of care for individuals who inject drugs and/or are sexually active and therefore at a higher risk of contracting HIV.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications.
Is Pre-Exposure Prophylaxis (PrEP) safe for humans?
PrEP, which uses medications like tenofovir disoproxil fumarate/emtricitabine, is generally considered safe based on clinical trials. Some mild side effects like nausea, vomiting, and diarrhea have been reported, and regular monitoring is recommended to prevent long-term issues with liver, kidneys, and bones.12345
How is the drug PrEP unique in preventing HIV?
PrEP is unique because it is taken by people who are not yet infected with HIV to prevent infection, using a combination of antiretroviral drugs like Truvada (tenofovir disoproxil fumarate and emtricitabine) before potential exposure to the virus. This proactive approach is different from treatments given after someone has already contracted HIV.678910
What data supports the effectiveness of the drug Pre-Exposure Prophylaxis (PrEP) for HIV prevention?
Who Is on the Research Team?
Jacqueline Hodges, MD, MPH
Principal Investigator
Duke Health
Mehri McKellar, MD
Principal Investigator
Duke Health
Are You a Good Fit for This Trial?
This trial is for individuals who inject drugs and/or are sexually active, putting them at a higher risk of contracting HIV. The study aims to provide oral HIV prevention medication via a medical van.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive oral PrEP pills to reduce their risk for contracting HIV
Follow-up
Participants are monitored for safety and effectiveness after treatment, including HIV status checks
What Are the Treatments Tested in This Trial?
Interventions
- Pre-Exposure Prophylaxis (PrEP)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Duke University
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator