Myoelectric Interface for Stroke Rehabilitation
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new training method called MINT (Myoelectric Interface for Neuromuscular Training), which uses muscle feedback to improve walking in stroke survivors. The trial compares two groups: one using MINT training on two leg muscles and another receiving a sham (inactive) treatment. It seeks participants who experienced a stroke affecting one side of their body at least six months ago, have significant trouble walking, but can still stand independently. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could enhance rehabilitation methods for stroke survivors.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does exclude those who have had spasticity treatment on the affected leg in the past 3 months or are participating in any pharmacological study within 6 weeks of enrollment.
What prior data suggests that the myoelectric interface is safe for stroke rehabilitation?
Research shows that MINT (Myoelectric Interface for Neurorehabilitation Training) is generally safe for stroke recovery. Studies have found that patients can use MINT safely and easily at home. Participants handled the treatment well, with no serious side effects reported. The treatment aims to improve leg function, aiding in walking and reducing unusual muscle activity. Early results are promising, suggesting MINT could be a useful tool for stroke recovery.12345
Why are researchers excited about this trial?
Researchers are excited about MINT Conditioning for stroke rehabilitation because it uses a novel approach by focusing on myoelectric training. Unlike traditional physical therapy, which often relies on repetitive exercises, MINT Conditioning targets the electrical signals from the brain to the muscles, potentially enhancing motor recovery by directly engaging the neural pathways. This method could offer a more precise and personalized rehabilitation experience, possibly leading to faster and more effective recovery for stroke patients.
What evidence suggests that MINT Conditioning is effective for stroke rehabilitation?
Research has shown that MINT conditioning, which participants in this trial may receive, can significantly improve walking in stroke survivors. Studies have found that it reduces muscle antagonism, enhancing movement and walking. This wearable technology can be used at home, allowing for daily use. Participants in earlier studies used the treatment regularly, indicating its effectiveness. Overall, these findings suggest that MINT conditioning could be a promising method to improve walking after a stroke.16789
Who Is on the Research Team?
Marc Slutzky, MD, PhD
Principal Investigator
Northwestern University
Are You a Good Fit for This Trial?
This trial is for adults aged 18-85 who have had a stroke at least 6 months ago, resulting in severe to moderate gait impairment. They must be able to stand unassisted and show abnormal muscle co-activation with clinically observable gait asymmetry. Excluded are those with metal implants, pacemakers, epilepsy, cognitive impairments that affect attention or understanding of instructions, visual impairments affecting game interaction, recent spasticity treatments on the affected leg, or other conditions that limit participation.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo MINT training to improve walking function
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- MINT Conditioning
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northwestern University
Lead Sponsor
University of Texas Southwestern Medical Center
Collaborator
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborator