Shear Wave Elastography for Tendinopathy
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to utilize Shear Wave Elastography (SWE) to study the viscoelastic properties of tendons to understand the functional differences between normal/asymptomatic and symptomatic tendon states. The study will also assess the degree of tendon healing following standard of care treatment.
Do I need to stop my current medications to join the trial?
The trial does not specify if you need to stop your current medications, but you cannot participate if you have a history of treatment with corticosteroids, estrogens, long-term quinolone antibiotics, or cholesterol drugs.
What safety data exists for PRP treatment in tendinopathy?
The safety of platelet-rich plasma (PRP) treatment for tendinopathy has been evaluated in several studies. These studies generally focus on the efficacy and potential complications of PRP injections, often guided by ultrasound. The research includes systematic reviews and meta-analyses, as well as pilot studies with long-term follow-up, which suggest that PRP is a promising treatment for tendinopathy with a focus on pain reduction and functional improvement. However, the progress in determining its efficacy and safety has been slow, and treatment complications are discussed in the context of concurrent therapies and platelet activation. Overall, PRP is considered a relatively safe treatment option, but further research is needed to fully understand its safety profile.12345
Is Ultrasound-guided Percutaneous Tenotomy with Platelet-Rich Plasma (PRP) a promising treatment for tendinopathy?
Yes, Ultrasound-guided Percutaneous Tenotomy with Platelet-Rich Plasma (PRP) is a promising treatment for tendinopathy. Studies show that it can help reduce pain and improve function in people with chronic tendinopathy by promoting healing and increasing collagen production, which is important for tendon repair.12367
What data supports the idea that Shear Wave Elastography for Tendinopathy is an effective treatment?
The available research shows that using platelet-rich plasma (PRP) injections, guided by ultrasound, can be effective in treating tendinopathy. Studies have demonstrated that PRP can help reduce pain and improve function in patients with chronic tendinopathy. For example, one study found that PRP injections led to pain reduction and functional improvement in patients with chronic tendinopathy. Another study highlighted that PRP can stimulate cell growth and collagen production, which are important for healing. Additionally, a systematic review and meta-analysis confirmed the effectiveness of PRP injections as a conservative treatment for tendinopathies. These findings suggest that PRP injections, when guided by ultrasound, can be a beneficial treatment option for tendinopathy.12358
Who Is on the Research Team?
David Reiter, PhD
Principal Investigator
Emory University
Are You a Good Fit for This Trial?
This trial is for individuals with a confirmed diagnosis of tendinopathy using ultrasound. It includes those experiencing lower extremity pain without tendon involvement and patients diagnosed clinically with tenalgia, which is pain in the tendons.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Shear wave elastography imaging is used to establish baseline measurements of viscoelastic properties of tendons among asymptomatic and symptomatic patients.
Treatment and Monitoring
Participants receive standard of care treatment and are monitored for changes in tendon healing using shear wave imaging and various assessment scales.
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Platelet-Rich Plasma Injection
- Ultrasound-guided Percutaneous Tenotomy with Platelet-Rich Plasma (PRP)
Ultrasound-guided Percutaneous Tenotomy with Platelet-Rich Plasma (PRP) is already approved in United States, European Union for the following indications:
- Chronic tendinopathy
- Tendinosis
- Chronic tendinopathy
- Tendinosis
Find a Clinic Near You
Who Is Running the Clinical Trial?
Emory University
Lead Sponsor