Use of Platelet-rich Plasma (PRP) Therapy in Patients With Brittle Nail Syndrome
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing a treatment where a patient's own blood is used to help heal and strengthen weak, breakable nails. The treatment aims to use special components in the blood to repair the nails.
Will I have to stop taking my current medications?
Yes, you must stop taking any medications at least 90 days before the study starts.
Is the treatment generally safe for humans?
How is platelet-rich plasma treatment different from other treatments?
Platelet-rich plasma (PRP) is unique because it uses a concentrated form of your own blood's platelets, which are rich in growth factors that can help repair and regenerate tissues. Unlike other treatments, PRP is derived from your own blood, making it an autologous (self-derived) therapy, and it has been shown to enhance cell growth and tissue healing in various medical fields.678910
What data supports the effectiveness of the treatment Platelet-poor plasma, Platelet-rich plasma?
Research on platelet growth factors, like thrombopoietin, shows they can effectively increase platelet production, which is important for treating conditions with low platelet counts. For example, oprelvekin, a platelet growth factor, has been shown to reduce the need for platelet transfusions in cancer patients undergoing chemotherapy.1112131415
Who Is on the Research Team?
Shari R Lipner, MD, PhD
Principal Investigator
Weill Medical College of Cornell University
Are You a Good Fit for This Trial?
Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive injections of platelet-rich plasma or platelet-poor plasma into the proximal nail folds
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Platelet-poor plasma
- Platelet-rich plasma
Find a Clinic Near You
Who Is Running the Clinical Trial?
Weill Medical College of Cornell University
Lead Sponsor
Eclipse Aesthetics, LLC
Collaborator