← Back to Search

Biological

Platelet Rich Plasma Injection for Knee Osteoarthritis

Phase < 1
Waitlist Available
Led By Christian Wuescher, MD
Research Sponsored by University of Toledo Health Science Campus
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Study Summary

This trial will be testing whether platelet-rich plasma injections can help ease pain for people with knee osteoarthritis.

Eligible Conditions
  • Osteoarthritis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Correlation of outcomes with whole blood and platelet rich plasma (PRP) concentrations
Functional status outcome using the Timed up and go (TUG) test, 1 year
Functional status outcome using the Timed up and go (TUG) test, 3 months
+9 more
Secondary outcome measures
Correlation of outcomes and patient demographics and co-morbidities
Emergency room utilization, 1 year
Emergency room utilization, 3 months
+6 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Participants receiving a platelet rich plasma injectionExperimental Treatment1 Intervention
All patients in the study will be receiving a platelet rich plasma injection, and we will be following their clinical outcomes
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Platelet Rich Plasma Injection
2016
N/A
~20

Find a Location

Who is running the clinical trial?

University of Toledo Health Science CampusLead Sponsor
40 Previous Clinical Trials
16,520 Total Patients Enrolled
1 Trials studying Osteoarthritis
60 Patients Enrolled for Osteoarthritis
Christian Wuescher, MDPrincipal InvestigatorUniversity of Toledo
Ashley Schneider, MDStudy DirectorUniversity of Toledo

Media Library

Platelet Rich Plasma Injection (Biological) Clinical Trial Eligibility Overview. Trial Name: NCT05080075 — Phase < 1
Osteoarthritis Research Study Groups: Participants receiving a platelet rich plasma injection
Osteoarthritis Clinical Trial 2023: Platelet Rich Plasma Injection Highlights & Side Effects. Trial Name: NCT05080075 — Phase < 1
Platelet Rich Plasma Injection (Biological) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05080075 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Washington
Other
Pennsylvania
Ohio
How old are they?
18 - 65
65+
What site did they apply to?
University of Toledo, Health Science Campus
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria

How responsive is this trial?

Most responsive sites:
  1. University of Toledo, Health Science Campus: < 24 hours
Typically responds via
Email
Average response time
  • < 1 Day
Recent research and studies
Brazilian Journal of AnesthesiologyJournal
Efetividade do plasma rico em plaquetas no tratamento da dor em osteoartrite de joelho: estudo comparativo randômico e duplo‐cego
Ghai, Babita, Vasudha Gupta, Ashish Jain, Nitika Goel, Devender Chouhan, and Yatinder Kumar Batra. 2019. “Efetividade do plasma rico em plaquetas no tratamento da dor em osteoartrite de joelho: estudo comparativo randômico e duplo‐cego”. Brazilian journal of anesthesiology. Elsevier BV. doi:10.1016/j.bjan.2019.06.003.
The American Journal of Sports MedicineJournal
Platelet-rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-blind, Randomized Controlled Trial
Di Martino, Alessandro, Berardo Di Matteo, Tiziana Papio, Francesco Tentoni, Filippo Selleri, Annarita Cenacchi, Elizaveta Kon, and Giuseppe Filardo. 2018. “Platelet-rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-blind, Randomized Controlled Trial”. The American Journal of Sports Medicine. SAGE Publications. doi:10.1177/0363546518814532.
Knee Surgery, Sports Traumatology, ArthroscopyJournal
Platelet-rich Plasma Intra-articular Injections for Cartilage Degeneration and Osteoarthritis: Single- Versus Double-spinning Approach
Filardo, Giuseppe, Elizaveta Kon, Maria Teresa Pereira Ruiz, Franca Vaccaro, Rita Guitaldi, Alessandro Di Martino, Annarita Cenacchi, Pier Maria Fornasari, and Maurilio Marcacci. 2011. “Platelet-rich Plasma Intra-articular Injections for Cartilage Degeneration and Osteoarthritis: Single- Versus Double-spinning Approach”. Knee Surgery, Sports Traumatology, Arthroscopy. Springer Science and Business Media LLC. doi:10.1007/s00167-011-1837-x.
Cell and Tissue ResearchJournal
The Use of PRP Injections in the Management of Knee Osteoarthritis
O’Connell, Brendan, Nicholas Martin Wragg, and Samantha Louise Wilson. 2019. “The Use of PRP Injections in the Management of Knee Osteoarthritis”. Cell and Tissue Research. Springer Science and Business Media LLC. doi:10.1007/s00441-019-02996-x.
All > Knee Osteoarthritis
~30 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top