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Contrast Agent

Exercise Pulmonary Transit Time Assessment for Heart Failure

Phase 4
Waitlist Available
Led By Ken Monahan, MD
Research Sponsored by Vanderbilt University Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age ≥ 18 years old
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3-10 seconds
Awards & highlights

Study Summary

This trial will use echocardiography to see if there is a difference in transit time before and after exercise.

Who is the study for?
This trial is for adults over 18 who can consent to participate. It's not suitable for pregnant or nursing individuals, or those with known allergies to specific ultrasound contrast agents like Definity or Optison.Check my eligibility
What is being tested?
The study is testing how well a technique called contrast echocardiography can measure the time it takes blood to travel through the lungs before and after exercise in people with heart failure.See study design
What are the potential side effects?
Potential side effects may include allergic reactions related to the ultrasound contrast used (Definity or Optison), such as shortness of breath, swelling, flushing, or changes in blood pressure.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3-10 seconds
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3-10 seconds for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Pulmonary Transit Time

Trial Design

1Treatment groups
Experimental Treatment
Group I: ExerciseExperimental Treatment1 Intervention
Everyone is in this arm
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
contrast echocardiography
2007
Completed Phase 4
~220

Find a Location

Who is running the clinical trial?

Vanderbilt University Medical CenterLead Sponsor
856 Previous Clinical Trials
672,178 Total Patients Enrolled
13 Trials studying Heart Failure
5,013 Patients Enrolled for Heart Failure
Ken Monahan, MDPrincipal InvestigatorVUMC
2 Previous Clinical Trials
117 Total Patients Enrolled

Media Library

Contrast Echocardiography (Contrast Agent) Clinical Trial Eligibility Overview. Trial Name: NCT04336995 — Phase 4
Heart Failure Research Study Groups: Exercise
Heart Failure Clinical Trial 2023: Contrast Echocardiography Highlights & Side Effects. Trial Name: NCT04336995 — Phase 4
Contrast Echocardiography (Contrast Agent) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04336995 — Phase 4

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Exercise Pulmonary Transit Time
Ken Monahan 2020. "Exercise Pulmonary Transit Time". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04336995.
~3 spots leftby Apr 2025
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