Functional electrical stimulation therapy. for Cervix Uteri

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Toronto Rehabilitation Institute - University Health Network, Toronto, Canada
Cervix Uteri+1 More
Functional electrical stimulation therapy. - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

Reduced arm and hand function has a significant impact on independence and quality of life after spinal cord injury. Functional electrical stimulation therapy (FES-T) is a treatment that can produce improvements in reaching and grasping function after neurological injuries. However, not all paralyzed muscles respond equally well to the therapy. Currently, therapists cannot predict which muscles will respond, limiting their ability to create a personalized therapy plan that can maximize outcomes while making the best use of the limited treatment time available. The objective of this study is to develop a diagnostic method that will allow therapists to quickly and easily screen muscles in the clinic, in order to predict how they will respond to FES-T. Participants with cervical spinal cord injury will receive FES-T through the Rocket Family Upper Extremity Clinic at the Toronto Rehabilitation Institute - University Health Network. Muscles receiving training will undergo a electrophysiological examination before the start of therapy, and will then be tracked for strength recovery over the course of 30 sessions. Lastly, signal processing and machine learning techniques will be applied to the electrophysiological data to predict the recovery profile of each muscle. The significance of this work will be to provide personalized therapy planning in FES-T, leading to more effective use of healthcare resource as well as improved outcomes.

Eligible Conditions

  • Cervix Uteri

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Muscle strength assessed at each of 30 therapy sessions (3-5 sessions per week).

Week 10
Surface electromyography signal features
Muscle strength assessed at each of 30 therapy sessions (3-5 sessions per week).
Muscle strength recovery profile

Trial Safety

Trial Design

1 Treatment Group

Functional electrical stimulation therapy
1 of 1
Experimental Treatment

10 Total Participants · 1 Treatment Group

Primary Treatment: Functional electrical stimulation therapy. · No Placebo Group · N/A

Functional electrical stimulation therapy
Device
Experimental Group · 1 Intervention: Functional electrical stimulation therapy. · Intervention Types: Device

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: muscle strength assessed at each of 30 therapy sessions (3-5 sessions per week).
Closest Location: Toronto Rehabilitation Institute - University Health Network · Toronto, Canada
Photo of Toronto 1Photo of Toronto 2Photo of Toronto 3
2015First Recorded Clinical Trial
0 TrialsResearching Cervix Uteri
3 CompletedClinical Trials

Who is running the clinical trial?

Wings for LifeOTHER
4 Previous Clinical Trials
753 Total Patients Enrolled
University Health Network, TorontoLead Sponsor
1,351 Previous Clinical Trials
471,623 Total Patients Enrolled
Sukhvinder Kalsi-Ryan, PhDPrincipal InvestigatorUniversity Health Network, Toronto
José Zariffa, PhDPrincipal InvestigatorUniversity Health Network, Toronto

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have paralysis or paresis in at least one upper extremity.
You have a minimum of 6 months post SCI.
You are able to tolerate being in a seated position for a least one hour required to deliver upper limb therapy.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.