Nicotine (electronic cigarette) for Smoking, Cigarette

Phase-Based Progress Estimates

Effectiveness

Safety

Smoking, Cigarette+2 More

Nicotine (electronic cigarette) - Other

You have a chance of qualifying for this trial. We made sure your application will take less than 5 minutes.

Eligibility

18+

All Sexes

What conditions do you have?

Select

Eligibility

18+

All Sexes

What conditions do you have?

Select

Study Summary

This trial will enroll 45 low-SES smokers and will provide them with either 8 weeks of complimentary e-cigarettes or nicotine pouches, or no intervention. The study will measure indicators of tobacco use and harm at baseline and Week 8.

Video Summary

Eligible Conditions

Smoking, Cigarette
Nicotine Dependence

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Smoking, Cigarette

Nicotine Replacement

Nicotine Oral Pouch

Cigarette A

Study Objectives

3 Primary · 5 Secondary · Reporting Duration: through study completion, an average of 6 months

Week 8

Change in 8-isoprostane from baseline to week 8

Change in Carbon monoxide from baseline to week 8

Change in NNAL from baseline to week 8

Change in cigarette dependence from baseline to week 8

Change in cigarettes per day from baseline to week 8

Body Weight Changes

Week 8.

Cigarette abstinence at week 8

Month 6

Feasibility and acceptability

Trial Safety

Safety Progress

1 of 3

Other trials for Smoking, Cigarette

Nicotine Replacement

Nicotine Oral Pouch

Cigarette A

Trial Design

3 Treatment Groups

Smoking As Usual

1 of 3

Electronic Cigarette

1 of 3

Nicotine Pouch

1 of 3

Active Control

Experimental Treatment

45 Total Participants · 3 Treatment Groups

Primary Treatment: Nicotine (electronic cigarette) · No Placebo Group · N/A

Electronic Cigarette

Other

Experimental Group · 1 Intervention: Nicotine (electronic cigarette) · Intervention Types: Other

Nicotine Pouch

Other

Experimental Group · 1 Intervention: Nicotine (nicotine pouch) · Intervention Types: Other

Smoking As UsualNoIntervention Group · 1 Intervention: Smoking As Usual · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline

Screening: ~3 weeks

Treatment: Varies

Reporting: through study completion, an average of 6 months

Who is running the clinical trial?

Brown UniversityLead Sponsor

408 Previous Clinical Trials

514,471 Total Patients Enrolled

8 Trials studying Smoking, Cigarette

771 Patients Enrolled for Smoking, Cigarette

Jasjit S Ahluwalia, MDPrincipal InvestigatorBrown University

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:

You have smoked cigarettes in the past 6 months.

You have a household income of less than $25,000 per year.

You are willing to substitute combustible cigarettes for EC or NPs.

About The Reviewer

Michael Gill - B. Sc.

First Published: October 12th, 2021

Last Reviewed: October 22nd, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.