Nicotine (electronic cigarette) for Smoking, Cigarette

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Smoking, Cigarette+2 More
Nicotine (electronic cigarette) - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will enroll 45 low-SES smokers and will provide them with either 8 weeks of complimentary e-cigarettes or nicotine pouches, or no intervention. The study will measure indicators of tobacco use and harm at baseline and Week 8.

Video Summary

Eligible Conditions
  • Smoking, Cigarette
  • Nicotine Dependence

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Smoking, Cigarette

Study Objectives

3 Primary · 5 Secondary · Reporting Duration: through study completion, an average of 6 months

Week 8
Change in 8-isoprostane from baseline to week 8
Change in Carbon monoxide from baseline to week 8
Change in NNAL from baseline to week 8
Change in cigarette dependence from baseline to week 8
Change in cigarettes per day from baseline to week 8
Body Weight Changes
Week 8.
Cigarette abstinence at week 8
Month 6
Feasibility and acceptability

Trial Safety

Safety Progress

1 of 3

Other trials for Smoking, Cigarette

Trial Design

3 Treatment Groups

Smoking As Usual
1 of 3
Electronic Cigarette
1 of 3
Nicotine Pouch
1 of 3
Active Control
Experimental Treatment

45 Total Participants · 3 Treatment Groups

Primary Treatment: Nicotine (electronic cigarette) · No Placebo Group · N/A

Electronic Cigarette
Other
Experimental Group · 1 Intervention: Nicotine (electronic cigarette) · Intervention Types: Other
Nicotine Pouch
Other
Experimental Group · 1 Intervention: Nicotine (nicotine pouch) · Intervention Types: Other
Smoking As UsualNoIntervention Group · 1 Intervention: Smoking As Usual · Intervention Types:

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: through study completion, an average of 6 months

Who is running the clinical trial?

Brown UniversityLead Sponsor
408 Previous Clinical Trials
514,471 Total Patients Enrolled
8 Trials studying Smoking, Cigarette
771 Patients Enrolled for Smoking, Cigarette
Jasjit S Ahluwalia, MDPrincipal InvestigatorBrown University

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have smoked cigarettes in the past 6 months.
You have a household income of less than $25,000 per year.
You are willing to substitute combustible cigarettes for EC or NPs.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 12th, 2021

Last Reviewed: October 22nd, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

Who else is applying?

What state do they live in?
New Jersey20.0%
Indiana20.0%
California20.0%
Other40.0%
How old are they?
18 - 65100.0%
What portion of applicants met pre-screening criteria?
Did not meet criteria100.0%