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Hormone Therapy

Vaginal Estrogen + Physical Therapy for Prolapse

N/A
Recruiting
Led By Pamela Moalli, MD, PhD
Research Sponsored by Pamela Moalli
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

Study Summary

This trial is testing whether adding vaginal estrogen to Pelvic Floor Physical Therapy (PFPT) can improve symptoms and support for women with mild pelvic organ prolapse.

Eligible Conditions
  • Pelvic Organ Prolapse

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Global impression of improvement in prolapse symptoms, using the PGI-I
Secondary outcome measures
Collagenase activity
Pelvic floor symptoms, using the PFDI-20
Pelvic organ prolapse stage, using the POP-Q exam
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Vaginal estrogenExperimental Treatment1 Intervention
Patients in the experimental group will receive vaginal estrogen cream
Group II: Placebo creamPlacebo Group1 Intervention
Patients in the comparison group will receive placebo vaginal cream

Find a Location

Who is running the clinical trial?

Pamela MoalliLead Sponsor
American Urogynecologic SocietyOTHER
10 Previous Clinical Trials
669 Total Patients Enrolled
National Institutes of Health (NIH)NIH
2,696 Previous Clinical Trials
6,952,535 Total Patients Enrolled

Media Library

Vaginal Estrogen (Hormone Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT01648751 — N/A
Vaginal Estrogen (Hormone Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01648751 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse
Pamela Moalli 2012. "Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01648751.
~4 spots leftby Apr 2025
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