← Back to Search

Dietary Supplement

Natural Supplements for Gulf War Syndrome

N/A

Recruiting

Led By Jarred Younger, PhD

Research Sponsored by University of Alabama at Birmingham

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5 minutes per report. this outcome will be assessed weekly, for up to 44 weeks.

Awards & highlights

Study Summary

This trial uses decentralized clinical trial design to identify effective treatments for Gulf War Illness (GWI). It tests 3 potential treatments & encourages geographically & demographically diverse participation from anywhere in the US.

Who is the study for?

This trial is for individuals with Gulf War Illness who can commit to a 10-month study and meet specific GWI case definitions. It's not suitable for those in other experimental studies, with abnormal liver or kidney function, pregnant women, or people with blood clotting disorders or on antiplatelet/anticoagulant medications.Check my eligibility

What is being tested?

The trial is testing the effectiveness of curcumin, resveratrol, and stinging nettle as treatments for GWI. Participants from across the U.S. can join this decentralized study without geographic restrictions.See study design

What are the potential side effects?

Potential side effects may include digestive issues due to curcumin; resveratrol might cause a reaction similar to estrogen; and stinging nettle could lead to mild stomach upset and allergic reactions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5 minutes per survey. this outcome will be assessed weekly, for up to 44 weeks.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5 minutes per survey. this outcome will be assessed weekly, for up to 44 weeks.

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5 minutes per survey. this outcome will be assessed weekly, for up to 44 weeks. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Veterans Rand 12-Item Health Survey (VR-12)

Secondary outcome measures

Number needed to treat (NNT)

Patient Global Impression of Change (PGIC)

Other outcome measures

Daily symptom report

Trial Design

3Treatment groups

Experimental Treatment

Group I: Gulf War Veterans, Stinging NettleExperimental Treatment1 Intervention

All GWI Veterans will undergo the same screening and experimental procedures. Participants must meet both the Kansas and CDC (Centers for Disease Control and Prevention) Case Definitions of GWI. Participants must have been deployed to the Persian Gulf Region during the 1990-1991 Gulf War, meet symptom domain criteria, and not have exclusionary medical conditions. The case definitions will be used for inclusionary screening purposes. This trial tests three interventions, which are all tested independently. Participants will receive only one of the three interventions. The curcumin, resveratrol, and stinging nettle trials all follow the same design and procedures. Participants will complete one month of baseline, eight months of capsules, and one month of endline measurements.

Group II: Gulf War Veterans, ResveratrolExperimental Treatment1 Intervention

Group III: Gulf War Veterans, CurcuminExperimental Treatment1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Curcumin

2017

Completed Phase 4

~1050

Resveratrol

2014

Completed Phase 3

~730

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor

1,590 Previous Clinical Trials

2,281,362 Total Patients Enrolled

1 Trials studying Gulf War Syndrome

54 Patients Enrolled for Gulf War Syndrome

Congressionally Directed Medical Research ProgramsFED

47 Previous Clinical Trials

6,278 Total Patients Enrolled

Jarred Younger, PhDPrincipal InvestigatorUniversity of Alabama at Birmingham

3 Previous Clinical Trials

63 Total Patients Enrolled

1 Trials studying Gulf War Syndrome

54 Patients Enrolled for Gulf War Syndrome

Media Library

Curcumin (Dietary Supplement) Clinical Trial Eligibility Overview. Trial Name: NCT05377242 — N/A

Gulf War Syndrome Research Study Groups: Gulf War Veterans, Curcumin, Gulf War Veterans, Resveratrol, Gulf War Veterans, Stinging Nettle

Gulf War Syndrome Clinical Trial 2023: Curcumin Highlights & Side Effects. Trial Name: NCT05377242 — N/A

Curcumin (Dietary Supplement) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05377242 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are any new participants currently being enrolled in this trial?

"Verified. As per the information on clinicaltrials.gov, this study is currently enrolling patients and was first published on May 31st 2023 as well as recently updated on June 16th 2023. 300 people are needed to be recruited from one medical centre in total."

Answered by AI

What is the current enrollment capacity for this trial?

"Affirmative. Clinicaltrials.gov shows that this research initiative, initially posted on May 31st 2023, is actively recruiting volunteers. 300 individuals need to be found from a single medical facility for the study's completion."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI

Jarred Younger 2023. "Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05377242.

All > Gulf War Illness