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Toothpaste with curcumin for Bad Breath

N/A
Waitlist Available
Led By Antonio Moretti, DDS, MS
Research Sponsored by University of North Carolina, Chapel Hill
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 21
Awards & highlights

Study Summary

This trial will compare the short-term clinical effect of curcumin-containing toothpaste on halitosis to placebo and will assess any potential shifts in the composition of dental biofilm associated with the use of curcumin-containing toothpaste.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 21
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 21 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Repeated Measures Regression of Volatile Sulphur Compounds (VSC)
Volatile Sulphur Compounds (VSC) at day 14
Volatile Sulphur Compounds (VSC) at day 21
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Toothpaste Containing CurcuminExperimental Treatment1 Intervention
After screening, participants will be randomly assigned to receive toothpaste that contains 0.5% curcumin.
Group II: Toothpaste Without CurcuminPlacebo Group1 Intervention
After screening, participants will be randomly assigned to receive toothpaste that does not contain curcumin.

Find a Location

Who is running the clinical trial?

University of North Carolina, Chapel HillLead Sponsor
1,504 Previous Clinical Trials
4,187,632 Total Patients Enrolled
Colgate PalmoliveIndustry Sponsor
88 Previous Clinical Trials
17,558 Total Patients Enrolled
Antonio Moretti, DDS, MSPrincipal InvestigatorUniversity of North Carolina, Chapel Hill
1 Previous Clinical Trials
50 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still openings for this medical experiment?

"According to the official listing on clinicaltrials.gov, recruitment is still open for this research project which was initially posted on May 24th 2022 and edited as recently as May 26th 2022."

Answered by AI

What qualifications must potential participants meet to be eligible for this trial?

"Those with halitosis who are between 18 and 65 years of age may be eligible to join this study. The medical team is aiming to recruit approximately 30 participants in total."

Answered by AI

Does this research encompass elderly persons in its recruitment?

"This trial is only open to adults aged 18-65, as specified in the eligibility criteria."

Answered by AI

How many test subjects are currently enlisted in this research project?

"Affirmative. The information submitted to clinicaltrials.gov implies that this medical research is presently seeking participants; the trial was initially posted on May 24th 2022, and its most recent update was recorded on May 26th 2022. At present, 30 people are needed between 1 sites for the study's completion."

Answered by AI

Who else is applying?

How old are they?
18 - 65
What portion of applicants met pre-screening criteria?
Did not meet criteria
Recent research and studies
clinicaltrials.govStudy
Effects of Curcumin-containing Toothpaste on Dental Biofilm and Associated Oral Halitosis
2022. "Effects of Curcumin-containing Toothpaste on Dental Biofilm and Associated Oral Halitosis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04998617.
~10 spots leftby Apr 2025
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