rTMS for Gulf War Syndrome
Trial Summary
Do I need to stop my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment rTMS for Gulf War Syndrome?
Research shows that repetitive transcranial magnetic stimulation (rTMS) can help reduce symptoms in conditions like PTSD, depression, and chronic pain, which are similar to symptoms experienced in Gulf War Syndrome. For example, rTMS has been effective in reducing PTSD symptoms in veterans and improving depressive symptoms in military personnel.12345
Is repetitive transcranial magnetic stimulation (rTMS) safe for humans?
Repetitive transcranial magnetic stimulation (rTMS) has been studied for safety in both healthy individuals and those with various brain conditions. While generally considered safe, it can cause side effects like seizures, especially at high intensities, and temporary hearing changes. Safety guidelines have been developed to minimize risks, and these guidelines have been updated over the years to ensure safe use.678910
How is the treatment rTMS unique for Gulf War Syndrome?
rTMS (Repetitive Transcranial Magnetic Stimulation) is unique for Gulf War Syndrome because it is a non-invasive treatment that uses magnetic fields to stimulate specific areas of the brain, which is different from traditional drug therapies. This method has been used for other conditions like depression and brain injury, offering a novel approach by directly targeting brain activity without medication.911121314
What is the purpose of this trial?
This study aims to look at the effectiveness of using repetitive transcranial magnetic stimulation (rTMS) in relieving pain and other co-morbid symptoms of Gulf War Illness.
Research Team
Albert Yick Leung, MD
Principal Investigator
VA San Diego Healthcare System, San Diego, CA
Eligibility Criteria
This trial is for Gulf War veterans under 65 who experience weekly headaches, muscle and joint pain, meet specific GWI criteria, and have a certain level of depression. It's not for those with pacemakers, metal in their body that affects MRI scans, major psychiatric conditions, other chronic pain states, history of seizures or brain injury.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive repetitive transcranial magnetic stimulation (rTMS) to alleviate pain and co-morbid symptoms of Gulf War Illness
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- rTMS
- Sham Transcranial Magnetic Stimulation
rTMS is already approved in United States, European Union for the following indications:
- Obsessive-Compulsive Disorder (OCD)
- Major Depressive Disorder
- Migraines
- Smoking cessation
- Obsessive-Compulsive Disorder (OCD)
- Major Depressive Disorder
Find a Clinic Near You
Who Is Running the Clinical Trial?
VA Office of Research and Development
Lead Sponsor