Bone grafting with collagen membrane for Peri-Implantitis

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Pittsburgh School of Dental Medicine, Pittsburgh, PAPeri-Implantitis+1 MoreInterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane) - Procedure
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will compare 2 surgical methods of treating peri-implantitis, to see which is more effective. Bone grafts and membranes may be used.

Eligible Conditions
  • Peri-Implantitis
  • Surgery

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

6 Primary · 1 Secondary · Reporting Duration: 12 months

12 months
Peri-Implant Bleeding on Probing
Peri-Implant Probing Depth
Radiographic Marginal Bone Loss (MBL)
Successful Treatment of Peri-Implantitis
2 weeks
Patient Reported Pain Outcomes
4 months
Clinical Peri-Implant Bone Defect Fill
Clinical Peri-Implant Bone Defect Resolution

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Bone grafting without collagen membrane
1 of 2
Bone grafting with collagen membrane
1 of 2

Active Control

Experimental Treatment

52 Total Participants · 2 Treatment Groups

Primary Treatment: Bone grafting with collagen membrane · No Placebo Group · N/A

Bone grafting with collagen membrane
Procedure
Experimental Group · 1 Intervention: InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane) · Intervention Types: Procedure
Bone grafting without collagen membrane
Procedure
ActiveComparator Group · 1 Intervention: InterOss Collagen (Bone xenograft) · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months

Who is running the clinical trial?

Andrea RavidaLead Sponsor
SigmaGraft Inc.UNKNOWN

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You must be in good overall health.

Who else is applying?

What state do they live in?
Virginia100.0%
What site did they apply to?
University of Pittsburgh School of Dental Medicine100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%

Frequently Asked Questions

Are there any openings available for participation in this clinical experiment?

"Affirmative. According to the information hosted on clinicaltrials.gov, recruitment for this experiment is still ongoing since its inception on January 1st 2023 and last modified date of January 16th 2023. The study requires 52 individuals to join at a single clinic site." - Anonymous Online Contributor

Unverified Answer

What is the scope of participation in this medical experiment?

"Correct. The clinical trial's listing on clinicaltrials.gov indicates that recruitment is ongoing, with the initial post having been made on January 1st 2023 and the last update being issued a fortnight later. This medical research requires 52 individuals to be enrolled from one centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.