← Back to Search

Corticosteroid

Cingal injection for Hip Osteoarthritis (ECHO Trial)

N/A

Waitlist Available

Research Sponsored by McMaster University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

ECHO Trial Summary

This trial will test the effects of Cingal, an injection used to treat knee osteoarthritis, on hip osteoarthritis.

Eligible Conditions

Hip Osteoarthritis

ECHO Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Patient reported hip pain as measured by Visual Analog Scale

Secondary outcome measures

Complications, including infection and other adverse events at 6-months post-injection.

Health-related quality of life (HRQL) as measured by the Short Form-12 questionnaire (SF-12)

Hip Function, as measured by the Hip Disability and Osteoarthritis Outcome Score (HOOS)

+2 more

Side effects data

From 2018 Phase 3 trial • 576 Patients • NCT03191903

12%

Headache

Viral upper respiratory tract infection

Injection site pain

Spinal pain

Upper respiratory tract infection

Toothache

Pyrexia

Hypoaesthesia

Abdominal Pain Upper

Bronchitis

Influenza

Laryngitis

Ear Pain

Diarrhea

Injection site reaction

Back pain

Pain in extremity

Migraine

Joint swelling

100%

80%

60%

40%

20%

Study treatment Arm

Cingal

Monovisc

Triamcinolone Hexacetonide (TH)

ECHO Trial Design

1Treatment groups

Experimental Treatment

Group I: Cingal injectionExperimental Treatment1 Intervention

Cingal will be administered by fellowship-trained physicians through ultrasound-guided injection using a 21-gauge needle into the joint space of the hip under sterile conditions. The needle track will be anesthetized with local anesthetic.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cingal

2020

Completed Phase 3

~1750

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Anika Therapeutics, Inc.Industry Sponsor

17 Previous Clinical Trials

2,822 Total Patients Enrolled

McMaster UniversityLead Sponsor

880 Previous Clinical Trials

2,597,728 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the age criteria for this research encompass individuals over 50 years of age?

"This clinical trial seeks out patients aged 40 and above, who have yet to reach 65 years of age."

Answered by AI

Could I be considered a viable participant in this research program?

"This clinical trial is seeking 100 individuals aged between 40 and 65 who suffer from hip osteoarthritis. For consideration, applicants must meet the prerequisites such as being adult males or females of a specified age range, having been diagnosed with mild to moderate OA based on imaging results (Tonnis grade 1-2), current use of NSAIDs/paracetamol for pain relief in the month prior to receiving Cingal, agreement to cease taking anti-inflammatory medication for two weeks before starting treatment through end of study period (6 months). Additionally, they must be able to comprehend the language used at their local medical site and provide"

Answered by AI

Are there any available openings to participate in this research?

"The clinical trial registry of clinicaltrials.gov reveals that this medical study is no longer recruiting subjects, as the last update was made on November 21st 2022 and it was initially posted on September 1st 2020. However, 649 other studies are currently enlisting participants."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Prospective Evaluation of the Cingal Injection for Hip Osteoarthritis

Olufemi Ayeni 2020. "A Prospective Evaluation of the Cingal Injection for Hip Osteoarthritis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04084704.