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Corticosteroid

Intra-articular Injections for Shoulder Osteoarthritis (GHOA Trial)

N/A

Recruiting

Research Sponsored by Rush University Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Baseline pain level of VAS greater than 4

Patient must be 18 years or older

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks

Awards & highlights

GHOA Trial Summary

This trial will compare two treatments for shoulder osteoarthritis to see which one is more effective to give relief and delay/avoid surgery.

Who is the study for?

This trial is for adults over 18 with primary glenohumeral osteoarthritis, which means they have significant shoulder joint pain and damage seen on X-rays. They must be experiencing a baseline pain level of more than moderate intensity. People who've had recent shoulder surgery, are pregnant, involved in workers' compensation cases for the shoulder, or have other types of arthritis or allergies to lidocaine can't participate.Check my eligibility

What is being tested?

The study aims to see if corticosteroid injections into the shoulder joint work better than platelet-rich plasma (PRP) injections for treating primary glenohumeral osteoarthritis without surgery. It's testing whether these treatments can relieve symptoms enough to delay or avoid shoulder replacement surgery.See study design

What are the potential side effects?

Possible side effects from the injections may include temporary increase in pain, infection at the injection site, allergic reactions to components like lidocaine, weakening of nearby bones or tendons, and less commonly systemic effects related to corticosteroids.

GHOA Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My pain level is more than 4 on a scale of 0-10.

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I am 18 years old or older.

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I have been diagnosed with shoulder arthritis through X-rays and doctor's exams.

GHOA Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Visual Analog Scale-Pain (VAS)

GHOA Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Corticosteroid Injection GroupExperimental Treatment1 Intervention

80mg Depo-Medrol and 8cc Lidocaine ultrasound-guided intra-articular injection

Group II: Platelet-Rich Plasma Injection GroupActive Control1 Intervention

15cc blood draw in Arthrex Autologous Conditioned Plasma (ACP) kit and processed per manufacturer instructions Ultrasound-guided intra-articular injection of isolated PRP

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Rush University Medical CenterLead Sponsor

422 Previous Clinical Trials

163,301 Total Patients Enrolled

1 Trials studying Shoulder Arthritis

200 Patients Enrolled for Shoulder Arthritis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still openings available for participants in this clinical trial?

"Affirmative. According to clinicaltrials.gov, this research study is currently seeking volunteers. The trial was initially published on March 13th 2023 and has since been revised on October 25th of the same year. 200 participants need to be enlisted from a single medical centre."

Answered by AI

To what extent has this medical experiment met its enrollment quota?

"Indeed, the clinicaltrials.gov website affirms that this research venture is actively recruiting participants. The study was first posted on March 13th 2023 and has received its most recent update on October 25th 2023. 200 people must be enrolled from a single medical centre for the trial to proceed."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)

2023. "Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04949087.