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Semaglutide for Obesity

N/A
Recruiting
Research Sponsored by University of California, Davis
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, midpoint (8-12 weeks), end of study (24 + 2 weeks)
Awards & highlights

Summary

This study aims to assess the impact of GLP-1 receptor agonists, semaglutide and tirzepatide, on food cravings and diet quality in individuals with overweight or obesity. Over 24 weeks, up to 150 adult participants will be monitored using questionnaires and dietary records at 0, 12, and 24 weeks to measure changes in diet quality, disordered eating, food cravings, and hunger. This research, conducted with Seen Medical Group at Knownwell Health Clinic, seeks to fill the gap in literature on the dietary quality effects of GLP-1RAs.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, midpoint (8-12 weeks), end of study (24 + 2 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, midpoint (8-12 weeks), end of study (24 + 2 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Food Craving Score
Secondary outcome measures
Change in USDA Healthy Eating Index-2015 (HEI) Score
Other outcome measures
Change in weight loss percentage
Changes in body fat percentage
Changes in resting metabolic rate (RMR)
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: TirzepatideExperimental Treatment4 Interventions
eligible patients who are prescribed tirzepatide for their obesity-management
Group II: SemaglutideExperimental Treatment4 Interventions
eligible patients who are prescribed semaglutide for their obesity-management
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Surveys
2020
Completed Phase 1
~11070

Find a Location

Who is running the clinical trial?

University of California, DavisLead Sponsor
919 Previous Clinical Trials
4,720,742 Total Patients Enrolled
30 Trials studying Obesity
33,569 Patients Enrolled for Obesity
KnownwellUNKNOWN
~100 spots leftby Sep 2025