Dysphagia Clinical Trials 2022

Browse 39 Dysphagia Medical Studies Across 35 Cities

59 Dysphagia Clinics

Reviewed by Michael Gill, B. Sc.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Lingual Endurance + Transference Exercisefor Ischemia

Cincinnati, OH
18+
All Sexes
This study will enroll 15 participants in each exercise condition (groups described below). Aim 1: Determine feasibility of lingual endurance training for individuals with persistent dysphagia after ischemic stroke. Primary outcome measures: patient adherence (# of attempted repetitions/# prescribed repetitions) and dose delivery (# of repetitions meeting goal/# prescribed repetitions). Aim 2: Determine efficacy of lingual endurance training on improving critical aspects of oropharyngeal swallowing (physiologic impairments, clearance of oropharyngeal residue, airway protection), functional oral intake, and patient reported swallowing quality of life in individuals with persistent dysphagia after ischemic stroke. Primary outcome measures: improvement on videofluoroscopic assessment of swallowing function using the gold standard Modified Barium Swallowing Impairment Profile (MBSImP) Overall Impairment (OI) score and Functional Oral Intake Scale (FOIS) score. Secondary outcome measures: oropharyngeal residue - Normalized Residue Ratio Scale (NRRS); airway invasion - Penetration Aspiration Scale (PAS). Patient reported outcome measures: EAT-10 (Eating Assessment Tool) and the Swallowing Quality of Life Questionnaire (SWAL-QoL). Aim 3: Determine if lingual endurance training + transference exercise (Exercise Group #2) results in better transference of exercise effects to the aforementioned outcomes of swallow safety and efficiency (in Aim2).
Recruiting
Has No Placebo
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Ice Chipsfor Deglutition Disorders

Morristown, NJ
18+
All Sexes
The objective of this study is to evaluate the effectiveness of early swallowing intervention in post extubated patients in the ICU to determine if this minimizes the risk of aspiration, increases initiating of oral intake sooner, reduced length of ICU stay and reduces the need for alternate means of nutrition/hydration. Patients will be randomly assigned to either Group A or B. We will decide grouping, using wheel that will randomly select group A or B after spinning. All participants will receive ongoing therapy while enrolled in the study until they receive an oral diet or are placed on a feeding tube as directed by their physician. Participants will be assigned to be in Group A or B. In Group A, participants will receive traditional swallowing therapy and perform exercises to strengthen swallowing muscles three times a day, while in Group B, participants will consume ice chips with supervision three times a day, which is also to strengthen swallowing muscles. Before starting therapy, all participants will receive a Clinical Dysphagia Evaluation by a Speech-Language Pathologist and an instrumental swallowing assessment by a Speech-Language Pathologist called a Fiberoptic Endoscopic Evaluation of Swallowing -(FEES). The FEES is an objective exam where a small, thin fiberoptic endoscope is placed trans nasally by the SLP. The assessment determines if a patient is aspirating, what texture of food and /or liquid the patient is aspirating, assesses ability to manage secretions, assesses vocal fold movement and determines if patient is safe to begin oral intake. Group A will serve as the control group. This group will receive oral hygiene followed by traditional dysphagia exercises, including effortful swallow, Masako Maneuver, and Tongue Press. This will occur three times a day. Group B will serve as the experimental group. In place of traditional dysphagia exercises, participants in Group B will receive oral hygiene and will consume small amounts of ice chips with supervision, three times a day. The ice chip protocol is based on the same findings as the Frazier Free Water Protocol, in that small amounts of clean water or ice chips are not harmful to the lungs and relatively benign if aspirated. Ice chips provide additional advantages in rehabilitating dysphagia as they are a cohesive bolus that are easier for patients with severe dysphagia to control in their mouth and swallow.
Recruiting
Has No Placebo
25 Dysphagia Clinical Trials Near Me
Cincinnati, OH
Morristown, NJ
San Francisco, CA
Sacramento, CA
More Trial Locations
An interactive map to display trial locations for Medical Sciences Building, Morristown Medical Center, UC San Francisco Medical Center, Voice and Swallow Center, UC Davis Medical Center, Department of Otolaryngology, and 30 more locations.
Most Popular References for Dysphagia Clinical Trials
Frequency
Citation
Top Hospitals for Dysphagia Clinical Trials
Location
Active Dysphagia Clinical Trials
All Time Trials for Dysphagia
First Recorded Dysphagia Trial
Trials
Edward Hines Jr. VA Hospital, Hines, IL, Hines, Illinois
2
2
2018
Medical Sciences Building, Cincinnati, Ohio
1
1
2022
Top Treatments for Dysphagia Clinical Trials
Treatment Name
Active Dysphagia Clinical Trials
All Time Trials for Dysphagia
First Recorded Dysphagia Trial
Trials
Lingual Endurance + Transference Exercise
1
1
2022
TOR-BSST© eLearning Training
1
1
2020
pharyngeal exerciser + standard therapy
1
1
2021
Pediatric Dysphagia Clinical Trials
Clinical Trial
Began Recruiting Date
Phase
Senior Friendly Dysphagia Clinical Trials

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 28th, 2021

Last Reviewed: August 30th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.