30 Participants Needed

Diaphragmatic Breathing for Esophageal Disorders

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Mayo Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how different positions and breathing techniques can strengthen the diaphragm and increase pressure at the esophagus junction, where the food pipe meets the stomach. The focus is on diaphragmatic breathing, a method of deep breathing using the muscle beneath the lungs. This technique aims to assist individuals already undergoing high-resolution esophageal manometry, a test that measures muscle pressure in the esophagus. Individuals who have not had esophageal or stomach surgery and do not have major illnesses or sinus issues affecting the test might be suitable candidates. As an unphased trial, this study offers a unique opportunity to contribute to understanding innovative breathing techniques that may enhance esophageal health.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this diaphragmatic breathing protocol is safe for esophageal disorders?

Research has shown that diaphragmatic breathing safely addresses certain health issues. For example, studies have found it can alleviate mental and digestive problems without causing harm. This technique has relieved symptoms of acid reflux and improved life quality for those with GERD, a condition where stomach acid often flows back into the throat. It also reduces belching and symptoms in people who do not respond well to acid-reducing medications. Overall, diaphragmatic breathing is well-tolerated, making it a safe choice for many.12345

Why are researchers excited about this trial?

Researchers are excited about diaphragmatic breathing for esophageal disorders because it offers a non-invasive, drug-free approach to managing these conditions. Unlike typical treatments that often involve medications or surgeries to improve esophageal function, this technique focuses on training patients to use their diaphragm more effectively. By improving muscle coordination and reducing stress on the esophagus, diaphragmatic breathing may help alleviate symptoms naturally. Researchers hope to find out if this method can provide lasting relief with fewer side effects and improve overall quality of life for patients.

What evidence suggests that diaphragmatic breathing is effective for esophageal disorders?

Research has shown that diaphragmatic breathing, which uses the diaphragm muscle located just below the lungs, can help with esophageal issues. Studies have found that this breathing technique strengthens the barrier preventing stomach acid from rising, reducing symptoms of acid reflux or GERD. By improving pressure in the stomach and esophagus, it helps manage reflux. Those who practice diaphragmatic breathing often experience fewer reflux symptoms and enjoy a better quality of life. In this trial, all participants will follow the diaphragmatic breathing protocol, which could effectively manage esophageal disorders.34678

Who Is on the Research Team?

AK

Andree Koop, MD

Principal Investigator

Mayo Clinic

Are You a Good Fit for This Trial?

This trial is for patients who are already scheduled to undergo high-resolution esophageal manometry, a test that measures muscle contractions in the esophagus. It's aimed at those with conditions like acid reflux or difficulty swallowing.

Inclusion Criteria

I am scheduled for or have had a detailed esophagus muscle test.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Manometry Assessment

Participants undergo high-resolution esophageal manometry to assess the optimal method of diaphragmatic breathing

1 session
1 visit (in-person)

Diaphragmatic Breathing Protocol

Participants perform a protocol assessing different techniques and positions for diaphragmatic breathing

1 session
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the manometry assessment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Diaphragmatic Breathing
Trial Overview The study is testing how diaphragmatic breathing affects pressure at the EGJ (the valve between the esophagus and stomach). Researchers want to find out which positions or maneuvers increase this pressure most effectively.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Diaphragmatic breathing protocolExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+

Citations

1.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/33009052/
Effects of Diaphragmatic Breathing on the Pathophysiology ...This study aimed to determine the effects of DB on reflux, lower esophageal sphincter (LES), and gastric pressures in patients with upright GERD ...
Positive effect of deep diaphragmatic breathing training on ...The results showed that during DEP, diaphragm mobility was significantly increased compared to calm breathing, indicating that the diaphragm ...
Effect of Diaphragmatic Breathing Training on the ...Diaphragmatic breathing training (DBT) may improve anti-reflux barrier function and reflux symptoms in patients with gastroesophageal reflux ...
The effect of breathing exercises on patients with GERDThis study showed that breathing exercises can help GERD patients reduce the symptoms of gastroesophageal reflux, improve their quality of life, and decrease ...
The effects of diaphragmatic breathing training on ...Diaphragmatic breathing training can alleviate symptoms and improve quality of life in patients with GERD.
Effect of Diaphragmatic Breathing Exercise, Jacobson's ...These techniques are safe and cost-effective treatment for addressing the psychological and gastrointestinal causes of NCCP.
Breathing Exercises in Patients With Gastroesophageal ...The aim of this study was to examine the effects of diaphragmatic breathing exercises combined with relaxation exercises on patient-reported reflux symptoms, ...
Diaphragmatic Breathing Reduces Belching and Proton ...We investigated whether diaphragmatic breathing therapy is effective in reducing belching and proton pump inhibitor (PPI)-refractory gastroesophageal reflux ...
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