Atrantil for Small Intestinal Bacterial Overgrowth

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Northwestern University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests the supplement Atrantil to determine its effectiveness for individuals with Intestinal Methane Overgrowth (IMO), a condition caused by excessive methane-producing bacteria in the gut. These bacteria can cause symptoms such as bloating, abdominal pain, and constipation. The trial aims to discover if Atrantil can reduce symptoms and improve quality of life for those affected. Individuals who frequently experience bloating and abdominal pain and are patients at Northwestern Memorial Hospital might be suitable candidates for this trial. As an unphased trial, this study provides a unique opportunity to contribute to scientific understanding and potentially find relief from uncomfortable symptoms.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Is there any evidence suggesting that Atrantil is likely to be safe for humans?

Research has shown that Atrantil is usually easy for people to take. In a past study involving individuals with irritable bowel syndrome with constipation, participants reported no side effects, indicating that the supplement is well-tolerated. Although Atrantil has no known side effects, some people might experience a "die-off" reaction. This occurs when harmful bacteria die off quickly, temporarily causing flu-like symptoms. Overall, Atrantil is considered safe and is certified gluten-free for those with sensitivities.12345

Why are researchers excited about this trial?

Atrantil is unique because it targets intestinal bacterial overgrowth with a blend of polyphenols, which are natural compounds found in plants. Unlike antibiotics that aim to kill bacteria, Atrantil works by reducing the production of methane gas in the gut, which can alleviate bloating and discomfort. This approach offers a plant-based alternative that may have fewer side effects and avoid the issue of antibiotic resistance. Researchers are excited about Atrantil's potential to provide relief while being gentle on the digestive system.

What evidence suggests that Atrantil might be an effective treatment for Intestinal Bacterial Overgrowth?

Research has shown that Atrantil may help alleviate symptoms of Intestinal Bacterial Overgrowth (IBO). In one study, 80% of patients experienced relief from bloating, constipation, and stomach discomfort after using Atrantil. Another report found an 88% success rate in reducing bloating and stomach pain. Atrantil targets certain gut bacteria, potentially lowering methane levels and improving symptoms. Early findings suggest it could be a promising alternative to antibiotics for some individuals. In this trial, participants will take two capsules of Atrantil three times a day for 28 days to further evaluate its effectiveness.26789

Who Is on the Research Team?

DB

Darren Brenner, MD

Principal Investigator

Northwestern Memorial Hospital/Feinberg School of Medicine

Are You a Good Fit for This Trial?

Inclusion Criteria

Participants must be able to provide informed consent
Participants must be able to attend study visits
Must have a diagnosis of Intestinal Methane Overgrowth based on North American Consensus/American College of Gastroenterology established cutoffs
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants take two capsules of Atrantil three times a day for 28 days

4 weeks
Daily self-administration

Follow-up

Participants are monitored for changes in quality of life and clinical symptoms after treatment

4 weeks
1 visit (in-person) for post-treatment assessment

What Are the Treatments Tested in This Trial?

Interventions

  • Atrantil
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Experimental: Atrantil (Medical Food)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Northwestern University

Lead Sponsor

Trials
1,674
Recruited
989,000+

Citations

Response of irritable bowel syndrome with constipation ...In this retrospective chart analysis of 24 patients administered Atrantil™, there was a 3.2-fold average improvement in abdominal pain, a 5.1-fold improvement ...
NCT04755673 | Atrantil for Intestinal Bacterial OvergrowthThe investigators propose to trial the supplement Atrantil on patients with IMO in order to study the supplements impact on symptoms, quality of life, and ...
Clinical TrialsThe trial showed that 80 percent of patients found relief after using Atrantil to control their bloating, constipation and abdominal discomfort. The results ...
Get Bloating Relief NaturallyAbsolutely! In clinical trials, Atrantil has been over 88% effective in providing relief from bloating, abdominal discomfort and constipation.
Dr. Ruscio's Insights on Atrantil: Benefits, Research, and ...In Dr. Ruscio's clinical experience, patients with chronic bloating, constipation, and abdominal discomfort often show marked improvement after ...
FAQsYes, Atrantil is FAARP gluten-free certified and safe for those with gluten sensitivities and intolerances. Is Atrantil allergy-friendly? Atrantil is free from ...
Healthcare ProfessionalsAlthough there are no known side effects with Atrantil, some patients may experience a Jarisch-Herxheimer reaction, also known as die-off. Die-off is ...
Atrantil for Intestinal Bacterial Overgrowth - ClinicalTrials.VeevaThe investigators propose to trial the supplement Atrantil on patients with IMO in order to study the supplements impact on symptoms, quality of life, and ...
ATRANTIL (90 Count)We have not had stomach pain as a reported side effect in our clinical trials. Atrantil is generally well tolerated. However, we cannot say that you may not ...
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