Mindfulness-Based Interventions for Obsessive-Compulsive Disorder
(MindOC Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications. However, if you are on medications for OCD, you must be on a stable dose for at least 8 weeks before starting the study.
What data supports the effectiveness of the treatment Mindfulness-Based Cognitive Therapy (MBCT) for Obsessive-Compulsive Disorder (OCD)?
Mindfulness-Based Cognitive Therapy (MBCT) has been shown to be effective in preventing relapse and treating various mental disorders, and it may help OCD patients who do not fully respond to traditional cognitive behavioral therapy (CBT). A pilot study suggests that MBCT could be a useful addition to CBT for OCD, helping patients manage symptoms and develop a better attitude towards their obsessions and compulsions.12345
Is mindfulness-based cognitive therapy (MBCT) safe for humans?
How is the treatment Mindfulness-Based Cognitive Therapy (MBCT) for OCD different from other treatments?
Mindfulness-Based Cognitive Therapy (MBCT) for OCD is unique because it combines mindfulness practices with cognitive therapy to help patients develop a more accepting attitude towards their obsessions and compulsive urges, potentially improving outcomes for those who do not fully respond to traditional Cognitive Behavioural Therapy (CBT). This approach may enhance the acceptability and effectiveness of treatment by integrating mindfulness, which is not typically a component of standard OCD therapies.14589
What is the purpose of this trial?
This trial is testing a new treatment called Mindfulness-Based Cognitive Therapy (MBCT) for people with Obsessive-Compulsive Disorder (OCD) who haven't fully benefited from standard treatments. MBCT helps patients become more aware of their thoughts and feelings without reacting to them, which can reduce OCD symptoms. If successful, this approach could be used widely in clinical settings to help more people with OCD. Mindfulness-Based Cognitive Therapy (MBCT) has been shown to be effective in various mental disorders and is now being explored as a complementary treatment for OCD, particularly for those who do not fully benefit from standard treatments.
Research Team
Neil A Rector, PhD
Principal Investigator
Sunnybrook Health Sciences Centre
Eligibility Criteria
This trial is for adults with OCD who have significant symptoms (YBOCS score > 17) and are stable on their current medication dose for at least 8 weeks. It's not suitable for those with severe mood disorders, schizophrenia, substance abuse issues, or urgent medical conditions.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive 12 weeks of mindfulness-based cognitive therapy or cognitive behaviour therapy
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Cognitive Behaviour Therapy (CBT)
- Mindfulness-Based Cognitive Therapy (MBCT)
Cognitive Behaviour Therapy (CBT) is already approved in European Union, United States, Canada for the following indications:
- Obsessive-compulsive disorder (OCD)
- Anxiety disorders
- Depression
- Obsessive-compulsive disorder (OCD)
- Anxiety disorders
- Depression
- Obsessive-compulsive disorder (OCD)
- Anxiety disorders
- Depression
Find a Clinic Near You
Who Is Running the Clinical Trial?
Sunnybrook Health Sciences Centre
Lead Sponsor
McMaster University
Collaborator
Canadian Institutes of Health Research (CIHR)
Collaborator
St. Joseph's Healthcare Hamilton
Collaborator