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Exercise for Obesity

N/A

Recruiting

Led By Robert C Hickner, PhD

Research Sponsored by Florida State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Women will be on combined estrogen/progestin hormonal contraceptive therapy (oral pill, transdermal patch or vaginal ring)

Women will be premenopausal

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from week 0 to week 8

Awards & highlights

Study Summary

This trial will study the effects of aerobic interval training on microvascular endothelial function in obese individuals.

Who is the study for?

This trial is for premenopausal women who are obese, sedentary, and have been weight stable for the last 6 months. They must meet at least three criteria of Metabolic Syndrome such as a large waist size or high blood pressure. Participants should not be taking certain medications or supplements that affect circulation or oxidative stress.Check my eligibility

What is being tested?

The study tests how an 8-week aerobic interval exercise program affects obesity-related endothelial dysfunction by reducing oxidative stress in muscles. It explores the role of NADPH oxidase activity and mitochondrial ROS in improving vascular health through exercise.See study design

What are the potential side effects?

Since this trial involves exercise as an intervention, potential side effects may include muscle soreness, fatigue, joint pain, and risk of injury related to physical activity. However, these are common reactions to new exercise routines.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am using a combined hormonal contraceptive method.

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I am a woman and have not gone through menopause.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from week 0 to week 8

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from week 0 to week 8

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from week 0 to week 8 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Reactive oxygen species (ROS)

Secondary outcome measures

Muscle blood flow

Trial Design

1Treatment groups

Experimental Treatment

Group I: Exercise trainingExperimental Treatment1 Intervention

Eight weeks of interval exercise training

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Exercise

2016

Completed Phase 1

~760

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Florida State UniversityLead Sponsor

199 Previous Clinical Trials

31,666 Total Patients Enrolled

16 Trials studying Obesity

1,393 Patients Enrolled for Obesity

Robert C Hickner, PhDPrincipal InvestigatorFlorida State University

1 Previous Clinical Trials

120 Total Patients Enrolled

1 Trials studying Obesity

120 Patients Enrolled for Obesity

Media Library

Exercise Clinical Trial Eligibility Overview. Trial Name: NCT04087655 — N/A

Obesity Research Study Groups: Exercise training

Obesity Clinical Trial 2023: Exercise Highlights & Side Effects. Trial Name: NCT04087655 — N/A

Exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT04087655 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are adults aged thirty and above able to participate in this experimental research?

"Patients aged 18 to 45 are eligible candidates for this research project."

Answered by AI

What is the size of the participant cohort for this research trial?

"Confirmed. From the information on clinicaltrials.gov, it is evident that this investigation is currently recruiting participants from one medical centre, with 25 volunteers required in total. It was initially posted on November 20th 2019 and last updated June 10th 2022."

Answered by AI

Are there still opportunities for people to join this experiment?

"Confirmed. The clinical trial, which was first publicised on November 20th 2019 is currently recruiting volunteers from one site and requires 25 participants in total. This data can be found on the aforementioned clinicaltrials.gov website as of June 10th 2022."

Answered by AI

Could I potentially partake in this experiment?

"The research project requires 25 individuals with clinically-defined obesity in the age bracket of 18 to 45. Race, gender or social background will not be considered as exclusionary factors for eligibility. Additionally, female participants must be premenopausal and on a combined estrogen/progestin hormone regimen (oral pill, patch or vaginal ring). Lastly, inactive obese people should have maintained their weight for the preceding 6 months before applying."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Microvascular Dysfunction in Obesity

Hickner 2019. "Microvascular Dysfunction in Obesity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04087655.