Treatment for Social Skills

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Vanderbilt University, Nashville, TN
Social Skills+4 More
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

Virtual Reality Training for Social Skills in Schizophrenia - Comparison With Cognitive Training

See full description

Eligible Conditions

  • Social Skills
  • Schizophrenia
  • Schizoaffective Disorders

Treatment Effectiveness

Study Objectives

This trial is evaluating whether Treatment will improve 2 primary outcomes and 4 secondary outcomes in patients with Social Skills. Measurement will happen over the course of Baseline and 5 weeks..

Baseline and 5 weeks.
Change in Social Attention: Social Engagement Latency (SEL)
Change in Social Brain Network Activity
Change in Social Emotion Recognition (BLERT)
Month 2
Change in Scale for the Assessment of Negative Symptoms (SANS)
Change in Scale for the Assessment of Positive Symptoms (SAPS)
Change in Social Outcome

Trial Safety

Trial Design

2 Treatment Groups

VR Social Skills Training
1 of 2
Healthy Controls
1 of 2
Active Control

This trial requires 56 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

VR Social Skills Training
Behavioral
Participants will undergo a virtual reality social skills training program for 10 sessions. Each session takes about an hour. Participants visit the lab twice a week. Therefore, the training duration is 5 weeks.
Healthy ControlsHealthy controls are recruited to yield comparison data. They do not undergo training.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline and 5 weeks. in addition, it will also be used to assess long term outcome 2 months after the training has ended.
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline and 5 weeks. in addition, it will also be used to assess long term outcome 2 months after the training has ended. for reporting.

Who is running the study

Principal Investigator
S. P.
Prof. Sohee Park, Professor of Psychology
Vanderbilt University

Closest Location

Vanderbilt University - Nashville, TN

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Inclusion

Patient Q&A Section

What are common treatments for schizophrenia?

"This research review shows that common forms of managing schizophrenia include antipsychotic medication, counseling regarding medication management, and the psychotropic medication. The research review also highlights common forms of antipsychotic drugs used in managing schizophrenia, the common methods of managing mood symptom, and the most common psychotropic drugs used to treat schizophrenia. To provide adequate patient education, it is important for psychiatrists to be able to distinguish different antipsychotic medications and mood symptom management treatments and the most common psychotropic medications used to treat the psychosis of schizophrenia." - Anonymous Online Contributor

Unverified Answer

How many people get schizophrenia a year in the United States?

"Approximately one case of schizophrenia is diagnosed annually in a population of over 330 million in the United States. This annual incidence of schizophrenia in most respects is within the range of that seen in the general population." - Anonymous Online Contributor

Unverified Answer

What causes schizophrenia?

"Despite the large effect of antipsychotics on cognitive functioning, this observation may well be spurious or reverse causal, i.e. they may not explain the underlying process(s)." - Anonymous Online Contributor

Unverified Answer

Can schizophrenia be cured?

"There has never been a cure for schizophrenia, despite the many different treatment methods used. Many treatments are available, and many research and clinical centers have attempted to find one that works. One problem is that a cure must be absolutely sure that the person is no longer suffering from a debilitating condition and that the treatment in question has healed the brain in such a way as to not only improve the outlook for the person but to reduce or eliminate the severity and/or duration of the symptoms that led to the illness. The most promising treatments focus on managing the schizophrenic symptoms: minimizing and controlling the positive psychosis (hallucinations, delusions, and distortions of consciousness) and reducing the negative symptoms (disturbances in communication, thinking, and mood)." - Anonymous Online Contributor

Unverified Answer

What is schizophrenia?

"Schizophrenia is a mental illness of unknown cause. It is characterized by hallucinations, delusions, disorganized or catatonic behavior and poverty of speech or speech disturbances. Schizophrenia is a severe disabling disease. The clinical manifestations vary greatly, however. Subjective and subjective psychotic symptoms in schizophrenia are subjective as such but are accompanied by objective symptoms such as sensory deficits or deficits in reasoning and behavior, and impaired cognitive functions. A few objective symptoms occur commonly in schizophrenia, but overall most other symptoms occur less often than in other psychotic disorders." - Anonymous Online Contributor

Unverified Answer

What are the signs of schizophrenia?

"Patients with schizophrenia do not display any specific facial expression. However, facial features such as lips are more rigid or tense in patients with psychotic schizophrenia compared to patients without psychotic schizophrenia. There may also be evidence for decreased facial symmetry in patients with psychotic schizophrenia." - Anonymous Online Contributor

Unverified Answer

Is treatment safe for people?

"Effective treatment can lead to improved health, less hospitalizations and better functioning and a longer life expectancy. Even for people with milder illnesses, good quality treatment can improve mental and physical functioning, and enhance quality of life, and can reduce relapse and hospitalization rates. In addition, people with schizophrenia who perceive higher levels of motivation and treatment as helpful and who receive regular psychosocial and psychiatric follow-up in their daily lives have significantly better social functioning and health-related quality of life than those who perceive lower levels of motivation and no follow-up. Effective treatment of psychosis may reduce the need for hospitalization and improve quality of life." - Anonymous Online Contributor

Unverified Answer

What is treatment?

"In the midst of the crisis of schizophrenia, the need to address the social exclusion experienced by those with schizophrenia is ever present, and it is therefore crucial for the recovery of persons with the illness to develop effective interventions to address social exclusion." - Anonymous Online Contributor

Unverified Answer

Has treatment proven to be more effective than a placebo?

"Although there is much debate in the scientific literature, studies that provide a control for the placebo effect, using an active versus a placebo and comparing the outcome of the study with an expectation of superiority to what would be found in a well-controlled randomized controlled clinical trial, have consistently shown that treatment is more effective than a placebo, if the treatments are appropriately designed. Therefore, there is no evidence to support the suggestion that treatment has been found to be less effective than a placebo. In contrast, there is compelling evidence that a control for the placebo effect may yield erroneous results." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of schizophrenia?

"Although the exact etiology of schizophrenia is not well understood, the vast majority of scholars agree that it is due to genetic and environmental factors in concert. Evidence has now demonstrated that schizophrenia is inherited in an autosomal recessive pattern, that is to say that both parents need to carry the gene for schizophrenia to have an affected child. This is in contrast to other psychiatric conditions, such as bipolar disorder or autism, for which only one affected parent is required for a child to inherit the disease. Because schizophrenia has such a specific pattern of transmission, it is often easy to distinguish the disease from other psychiatric disorders." - Anonymous Online Contributor

Unverified Answer

What are the latest developments in treatment for therapeutic use?

"The recent advances in treatment for schizophrenia in our country, by improving the pharmacotherapy, are an important development. The recent drugs such as olanzapine, risperidone, aripiprazoles, haloperidol and clozapine have reduced the use of first line antipsychotics and increased the use of newer drugs. While not effective as olanzapine, aripiprazole and clozapine are used as a second line treatment for acute episodes. Findings from a recent study of the randomized studies reveal that these newer drugs show improvement in the symptoms of those with serious psychotic illnesses when compared with older and traditional antipsychotic drugs." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating schizophrenia?

"No new treatments were found to date so we conclude that while schizophrenia remains the biggest unmet medical need in history, there are no new treatments in the foreseeable future." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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