← Back to Search

Amino Acid Supplements for Muscle Building Post-Exercise (DiEx Trial)

N/A
Waitlist Available
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 60 minutes
Awards & highlights

DiEx Trial Summary

This trial investigates how different amino acid supplements affect muscle building & breakdown during resistance training. Results could benefit athletes & those with muscle wasting.

Who is the study for?
This trial is for trained individuals who've been doing structured exercises like weightlifting or team sports at least twice a week for the past three months. It's not suitable for those unable to follow the study rules, with certain medical conditions, on medications affecting protein metabolism, using illicit drugs or tobacco, amenorrheic women, or those taking supplements that could interfere with results.Check my eligibility
What is being tested?
The study compares the muscle-building effects of three supplements after resistance exercise: BCAA Supplement, Collagen Supplement and Di-Leucine Supplement. Using a 'breath test', blood and urine samples will help understand which supplement best promotes muscle growth and prevents breakdown.See study design
What are the potential side effects?
While specific side effects are not detailed in this summary, potential risks may include digestive discomfort from the supplements and typical post-exercise soreness or fatigue.

DiEx Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 60 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Whole-Body Protein Synthesis
Secondary outcome measures
Murine Cell-Based Experiments (ex-vivo experiments) - Protein Synthesis
Murine Cell-Based Experiments (ex-vivo experiments) - mTORC1 Signalling
Murine Cell-Based Experiments (ex-vivo experiments) -hypertrophy
+1 more

DiEx Trial Design

3Treatment groups
Experimental Treatment
Group I: Di-Leucine supplementExperimental Treatment1 Intervention
Participants will consume a amino acid supplement containing Di-Leucine following resistance exercise and their whole body anabolism will be determined over the subsequent 6 hours
Group II: Collagen SupplementExperimental Treatment1 Intervention
Participants will consume a amino acid supplement containing collagen protein following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Group III: BCAA SupplementExperimental Treatment1 Intervention
Participants will consume a amino acid supplement containing branched chain amino acids (BCAA) following resistance exercise and their whole body anabolism will be determined over the subsequent hours
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
BCAA Supplement
2017
N/A
~30
Collagen Supplement
2020
N/A
~110

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
689 Previous Clinical Trials
1,018,631 Total Patients Enrolled

Media Library

Di-Leucine supplement Clinical Trial Eligibility Overview. Trial Name: NCT05754125 — N/A
Interventional. Research Study Groups: Di-Leucine supplement, BCAA Supplement, Collagen Supplement
Interventional. Clinical Trial 2023: Di-Leucine supplement Highlights & Side Effects. Trial Name: NCT05754125 — N/A
Di-Leucine supplement 2023 Treatment Timeline for Medical Study. Trial Name: NCT05754125 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there currently any open enrollment opportunities in this clinical trial?

"Affirmative, according to the clinicaltrials.gov records this trial is actively recruiting patients. Initially posted on 1/21/2023 and updated on 2/21/2023, a total of 12 participants need to be sourced from one medical centre for this study."

Answered by AI

How many subjects are receiving treatment through this investigation?

"Affirmative. Records published on clinicaltrials.gov demonstrate that this medical research is currently seeking volunteers, with 12 participants needed from a single site. The initial post date was January 21st 2023 and the most recent update occured February 21st of the same year."

Answered by AI

Do the qualifications for this experiment include people of a younger age demographic?

"In order to be eligible for this medical trial, the age of participants must fall between 18 and 35 years old."

Answered by AI

Who is eligible to take part in this clinical investigation?

"The parameters for admission to this research study stipulate that participants must be interventional and fall within an age range of 18-35. Approximately 12 people are being recruited into the trial."

Answered by AI
~6 spots leftby Apr 2025