Myeloma Clinical Trials
Here are the 6 most popular medical studies for myeloma
Behavioural Intervention
Home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching for Multiple Myeloma
This clinical trial tests the effectiveness of a home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching to decrease fatigue and improve quality of life in older patients with multiple myeloma (MM). Studies have shown that MM patients have the highest symptom burden among all blood cancers, with older patients experiencing more symptoms and problems, such as fatigue and decreased quality of life, compared to younger patients. There is some data to support that physical activity may have beneficial effects on fatigue, physical function, and quality of life in older cancer patients. Studies have also shown that older patients prefer activities that are gentle, holistic, and home-based. Mindfulness-based interventions have been shown to have positive effects on sleep, depression, anxiety and cancer-related fatigue. Health coaching is a patient centered behavioral change intervention that is delivered by various healthcare professionals and involves goal-setting, self-discovery, and accountability. Health coaching interventions have been shown to increase physical activity levels and improve quality of life. A home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching may decrease fatigue and improve the quality of life in older patients with MM.
Multiple Myeloma Screening and Patient Navigation Program for Multiple Myeloma
This trial seeks to develop a program to better understand and detect multiple myeloma early, including analyzing community understanding and participation in screening, and providing patient navigation for those with abnormal results. #MM #Screening
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Metastatic Myeloma Clinical Trials
View 99 metastatic myeloma medical studies.
CRM1 Inhibitor
Selinexor + Daratumumab + Carfilzomib + Dexamethasone for Multiple Myeloma
This trial is testing the effect of adding selinexor to a regimen of carfilzomib, daratumumab, and dexamethasone for patients with high-risk multiple myeloma that has returned or stopped responding to treatment.
Monoclonal Antibodies
Belantamab Mafodotin for Multiple Myeloma
This trial is testing a new drug, belantamab mafodotin, as a possible treatment for multiple myeloma that has returned or does not respond to other treatments. The drug will be given as an IV on day 1 of each cycle, and the trial will last for 56 days.
BCMA Positive Clinical Trials
View 6 BCMA positive medical studies.
Monoclonal Antibodies
Belantamab Mafodotin for Multiple Myeloma
This trial is testing a new drug, belantamab mafodotin, as a possible treatment for multiple myeloma that has returned or does not respond to other treatments. The drug will be given as an IV on day 1 of each cycle, and the trial will last for 56 days.
Monoclonal Antibodies
Elranatamab + Carfilzomib + Dexamethasone + Maplirpacept for Multiple Myeloma
This trial is testing a combo of medicines to treat multiple myeloma, a form of cancer in the bone, in people 18+ who have received 1-3 lines of therapy. Meds will be given for 2 yrs & monitored for safety.
Phase 3 Myeloma Clinical Trials
View 99 phase 3 myeloma medical studies.
Monoclonal Antibodies
Daratumumab + Lenalidomide + Dexamethasone for Multiple Myeloma
This trial will compare two treatments for people with newly diagnosed multiple myeloma who are not candidates for high-dose chemotherapy and stem cell transplant. The first treatment is daratumumab in combination with lenalidomide and dexamethasone. The second treatment is lenalidomide and dexamethasone. The study will look at how well each treatment works in terms of progression-free survival (PFS).
View More Myeloma Trials
See another 70 many medical studies focused on myeloma.
Frequently Asked Questions
Introduction to myeloma
What are the top hospitals conducting myeloma research?
When it comes to innovative clinical trials in the treatment of myeloma, several leading hospitals are pushing boundaries and offering hope. Memorial Sloan Kettering Cancer Center in New York is at the forefront with 12 active myeloma trials, demonstrating their commitment to finding breakthroughs for this challenging condition. While they may not have any previous myeloma trials on record, their dedication to ongoing research sets them apart. In Denver, the Colorado Blood Cancer Institute is making significant strides with nine current myeloma trials. The absence of past trials does not diminish their efforts in advancing treatment options for patients with this blood cancer.
The Mayo Clinic in Rochester is also actively involved in tackling myeloma through eight ongoing clinical trials. Their expertise and experience across various medical specialties make them a trusted institution when it comes to exploring new avenues for treating this disease. Similarly, the Levine Cancer Institute in Charlotte ensures that six active clinical trials are underway to provide patients with cutting-edge options and improved outcomes.
Notably, Massachusettsn New York is at the forefront with 12 active myeloma trials, demonstrating their commitment to finding breakthroughs for this challenging condition. While they may not have any previous myeloma trials on record, their dedication to ongoing research sets them apart. In Denver, the Colorado Blood Cancer Institute is making significant strides with nine current myeloma trials. The absence of past trials does not diminish their efforts in advancing treatment options for patients with this blood cancer.
The Mayo Clinic in Rochester is also actively involved in tackling myeloma through eight ongoing clinical trials. Their expertise and experience across various medical specialties make them a trusted institution when it comes to exploring new avenues for treating this disease. Similarly, the Levine Cancer Institute in Charlotte ensures that six active clinical trials are underway to provide patients with cutting-edge options and improved outcomes.
Notably, Massachusetts General Hospital in Boston contributes its expertise by conducting five active myeloma trials despite having no all-time records so far.These esteemed institutions illustrate how collaboration between dedicated researchers leads us closer towards effective treatments for those battling against myeloma—an aggressive form of blood cancer characterized by abnormal plasma cell growth within bone marrow.The collective effort made by these top hospitals instills hope among patients worldwide while reinforcing our belief that scientific advancements hold immense potential to transform lives affected by such diseases as we collectively strive toward a healthier tomorrow
Which are the best cities for myeloma clinical trials?
When it comes to myeloma clinical trials, several cities are at the forefront of research and development. New York leads the way with 55 active trials focusing on treatments like CC-95266, bb2121, and ISB 1342. Denver follows closely behind with 43 ongoing studies investigating medications such as Lenalidomide. New Yo to myeloma clinical trials, several cities are at the forefront of research and development. New York leads the way with 55 active trials focusing on treatments like CC-95266, bb2121, and ISB 1342. Denver follows closely behind with 43 ongoing studies investigating medications such as Lenalidomide, Bortezomib, and Cohort D1 and D2: maplirpacept (PF-07901801) + an anti-CD20 targeting agent. Lastly, Boston and Atlanta both offer promising opportunities for myeloma patients with 31 and 29 active trials respectively examining various treatment approaches including Isatuximab SAR650984, Belantamab mafodotin, TEG002, Lenalidomide, ixazomib,and bb2121. These cities serve as hubs for cutting-edge clinical research that can potentially improve outcomes for individuals battling myeloma.
Which are the top treatments for myeloma being explored in clinical trials?
Clinical trials for myeloma are uncovering promising treatments that hold potential for patients fighting this challenging disease. One standout therapy is daratumumab, currently being investigated in multiple trials and showing encouraging results. Another contender making waves is belantamab mafodotin, with its innovative approach gaining attention in ongoing research studies. Finally, lenalidomider myeloma are uncovering promising treatments that hold potential for patients fighting this challenging disease. One standout therapy is daratumumab, currently being investigated in multiple trials and showing encouraging results. Another contender making waves is belantamab mafodotin, with its innovative approach gaining attention in ongoing research studies. Finally, lenalidomide has proven its worth over time and remains a top option under investigation as well. These three treatments are at the forefront of myeloma clinical trials, offering hope for improved outcomes and quality of life for patients in the future.
What are the most recent clinical trials for myeloma?
Exciting advancements are occurring in the realm of myeloma treatment, with recent clinical trials providing promising findings. Notable studies include Arm A, a Phase 3 trial exploring new therapeutic approaches for myeloma patients. Additionally, Teclistamab, an investigational therapy currently in Phase 3 clinical trials, shows potential as a treatment option. Another trial worth mentioning is KTX-1001, which is investigating innovative methods to combat myeloma and has entered Phase 1. These trials signify significant progress towards improving outcomes and enhancing quality of life for individuals affected by this disease.
What myeloma clinical trials were recently completed?
Recent clinical trials focusing on myeloma have made significant strides in advancing treatments for this challenging condition. In October 2021, a trial sponsored by Washingtonn myeloma have made significant strides in advancing treatments for this challenging condition. In October 2021, a trial sponsored by Washington University School of Medicine concluded, evaluating the effectiveness of Uproleselan against myeloma. Another notable trial completed in September 2021 was led by the National Cancer Institute and investigated mRNA-1273 as a potential therapy option. Additionally, AgenTus Therapeutics wrapped up their agenT-797 study in January 2021. These exciting developments highlight the commitment of researchers to find innovative solutions for myeloma patients.