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Optical Spectroscopy for Cervical Cancer Detection

N/A

Recruiting

Led By Nimmi Ramanujam, Ph.D.

Research Sponsored by Duke University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients undergoing LEEP for the treatment of cervical cancer in early stages

Patients undergoing colposcopy for the diagnosis of cervical cancer

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day of procedure (less than 10 minutes)

Awards & highlights

Study Summary

This trial will use optical technologies to look for signs of cervical dysplasia.

Who is the study for?

This trial is for women undergoing colposcopy, LEEP procedures, or follow-up Pap smears for cervical cancer diagnosis and treatment. It's not open to those under 18, anyone unable to consent, or patients with recent bleeding or preterm labor.Check my eligibility

What is being tested?

The study is testing optical technologies like a bench-top system, portable spectrometer, and transvaginal colposcope to identify the unique optical patterns of precancerous changes in the cervix.See study design

What are the potential side effects?

Since this trial involves diagnostic procedures rather than medications, side effects are minimal but may include discomfort from the use of the devices during examination.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am receiving LEEP for early-stage cervical cancer.

Select...

I am having a colposcopy to check for cervical cancer.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day of procedure (less than 10 minutes)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day of procedure (less than 10 minutes)

This trial's timeline: 3 weeks for screening, Varies for treatment, and day of procedure (less than 10 minutes) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Identification of optical signatures of cervical tissue

Trial Design

1Treatment groups

Experimental Treatment

Group I: ColposcopeExperimental Treatment3 Interventions

Patients referred for GYN procedures. Specifically, patients will be referred for Pap smear, colposcope or LEEP. The intervention for this arm is the use of the bench-top, miniature optical spectrometer or trans-vaginal colposcope

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor

2,360 Previous Clinical Trials

3,419,980 Total Patients Enrolled

Nimmi Ramanujam, Ph.D.Principal InvestigatorDuke University

2 Previous Clinical Trials

715 Total Patients Enrolled

Media Library

Portable Optical Spectrometer Clinical Trial Eligibility Overview. Trial Name: NCT00900575 — N/A

Cervical Cancer Research Study Groups: Colposcope

Cervical Cancer Clinical Trial 2023: Portable Optical Spectrometer Highlights & Side Effects. Trial Name: NCT00900575 — N/A

Portable Optical Spectrometer 2023 Treatment Timeline for Medical Study. Trial Name: NCT00900575 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there currently a recruitment for participants in this experiment?

"Affirmative, the information present on clinicaltrials.gov demonstrates that this study is recruiting participants. This trial was announced on May 1st 2006 and has been revised recently as of April 15th 2022. 350 individuals are needed at a single site to complete this research project."

Answered by AI

To what extent is the populace participating in this experiment?

"Affirmative. According to information found on clinicaltrials.gov, this research endeavour is currently recruiting participants with its first post dating back to May 1st 2006 and the last update being on April 15th 2022. 350 individuals are expected at a single medical site."

Answered by AI

Recent research and studies

NeoplasiaJournal

Quantitative Physiology of the Precancerous Cervix in Vivo Through Optical Spectroscopy

Chang, Vivide Tuan-Chyan, Peter S. Cartwright, Sarah M. Bean, Greg M. Palmer, Rex C. Bentley, and Nirmala Ramanujam. 2009. “Quantitative Physiology of the Precancerous Cervix in Vivo Through Optical Spectroscopy”. Neoplasia. Elsevier BV. doi:10.1593/neo.81386.

Scientific ReportsJournal

A Novel Speculum-free Imaging Strategy for Visualization of the Internal Female Lower Reproductive System

Asiedu, Mercy N., Júlia S. Agudogo, Mary E. Dotson, Erica Skerrett, Marlee S. Krieger, Christopher T. Lam, Doris Agyei, et al.. 2020. “A Novel Speculum-free Imaging Strategy for Visualization of the Internal Female Lower Reproductive System”. Scientific Reports. Springer Science and Business Media LLC. doi:10.1038/s41598-020-72219-9.

clinicaltrials.govStudy

Cervical Cancer Detection Using Optical Spectroscopy

2006. "Cervical Cancer Detection Using Optical Spectroscopy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00900575.

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