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Dealcoholized Muscadine Wine for Skin Health

N/A
Waitlist Available
Led By Liwei Gu, PhD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Must not have
History of skin cancer
Sunbathing or the use of tanning bed
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 28 days
Awards & highlights
No Placebo-Only Group

Summary

This trial will study the effects of dealcoholized muscadine wine on oxidative stress, inflammation, skin photoaging, and the gut microbiome in women.

Who is the study for?
This trial is for healthy women aged 40-67 with a BMI of 20.0-29.9 and Fitzpatrick skin types 2 or 3. It's not suitable for those who are pregnant, breastfeeding, smoke, consume alcohol, have a history of skin cancer, use certain medications that could affect the study results, sunbathe frequently or use tanning beds, or take vitamin/mineral supplements.
What is being tested?
The trial is testing if drinking dealcoholized muscadine wine daily for six weeks can reduce oxidative stress and inflammation in the body, improve skin health against aging from sunlight exposure (photoaging), and positively change gut bacteria compared to a control group drinking sugar water.
What are the potential side effects?
Since this trial involves dealcoholized wine which is non-alcoholic and similar to grape juice in composition; side effects might be minimal but could include digestive changes due to alterations in gut microbiome.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I have had skin cancer in the past.
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I do not sunbathe or use tanning beds.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 28 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 28 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change from baseline Skin color after UV radiation
Change from baseline skin erythema and melanin index
Change from baseline skin hydration
+3 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: Dealcoholized Muscadine WineActive Control2 Interventions
Participants in this arm will receive 300ml of dealcoholized muscadine wine daily for six weeks. After a 7- day run-in period, participants will receive dealcoholized muscadine wine daily for six weeks
Group II: Control BeverageActive Control2 Interventions
Participants in this arm will receive 300 ml of sugar water and acid content for six weeks. After a 7-day run in period, participants will receive sugar water for six weeks.

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Who is running the clinical trial?

University of FloridaLead Sponsor
1,384 Previous Clinical Trials
762,567 Total Patients Enrolled
2 Trials studying Skin Health
42 Patients Enrolled for Skin Health
Liwei Gu, PhDPrincipal InvestigatorUniversity of Florida
6 Previous Clinical Trials
320 Total Patients Enrolled
1 Trials studying Skin Health
22 Patients Enrolled for Skin Health
~4 spots leftby Oct 2025
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