Treatment for Skin Health

Recruiting · 18+ · Female · Gainesville, FL

This study is evaluating whether cranberry juice may help improve skin health in women.

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About the trial for Skin Health

Treatment Groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.

Control Group 1
Placebo juice
Cranberry juice
Control Group 2
Placebo juice
Cranberry juice


This trial is for female patients aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
BMI (18.5-29.9)
Body weight ≥110 pounds
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: Baseline, 28 days
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: Baseline, 28 days.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Treatment will improve 8 primary outcomes and 1 secondary outcome in patients with Skin Health. Measurement will happen over the course of 24 hours.

Survival rate of human keratinocyte under UV light
The immortalized human keratinocyte cell line (HaCaT) will be cultured in Dulbecco's Modified Eagle Medium. Cells will be incubated with human serum collected after 2-hour and 4-hour cranberry juice intake or water intake for 24 hours.
Change from baseline Skin color change after UV irradiation at 28 days
Irradiation will be applied to dorsal skin (region not typically exposed to the sun) using an FDA approved UVB phototherapy light and a UV light meter. At each assessment, skin color will be measured before and 24 h after irradiation. Skin color will be evaluated by a colorimeter using the 3-dimensional color system with L-, a-, and b-values. L- and b- values assess lightness and browning effects, respectively. The a-value (red/green-axis) is a measure for reddening (erythema). The Δa-values (a-value 24 h after irradiation minus a-value before irradiation) will compared between baseline through 3 months; decreasing Δa-values indicates a photoprotective effect.
Change from baseline hydration
Skin hydration will be measured with a Corneometer (CK Electronic GmbH, Germany. This is a handheld probe that allows for quick and easy measurements.
Change from baseline Skin transepidermal water loss
Skin transepidermal water loss an will be measured using a Tewameter (CK Electronic GmbH, Germany). This is a handheld probes that allow for quick and easy measurements
Change in skin lipidome
Stratum corneum layer on forearm skin will be sampled with 16 D-squame® tapes using a standard noninvasive tape stripping technique. This will be sent for lipidomic analysis
Change from baseline SELS parameters
SELS (Surface evaluation of the Living Skin) parameters, including smoothness, roughness, scaliness, and wrinkles, will be determined using a Visioscan VC20. This hand-hold device scans a 1 cm x 1 cm skin area ( Visioscan VC20 scanner consists of a camera, a high- resolution video sensor, and a UVA light no hazardous to human skin.
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Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many people get skin health a year in the United States?

5.7 million US adults have a skin condition at some point during a given year. Dermatologists diagnose up to 60.1 million adults with skin health the year. At least 17% of adults seek medical care for at least one skin problem in a given year. People with skin health most frequently have some sort of acne or eczema in a given year.

Anonymous Patient Answer

What are the signs of skin health?

There are a variety of symptoms that can be due to skin problems, and a person with a skin problem should be screened for an underlying skin health concern. A skin examination should be considered in each new case when the referral pattern of history is suggestive of an underlying skin disease.\n

Anonymous Patient Answer

What are common treatments for skin health?

It is important for dermatologic patients to know the common treatments for skin conditions in order to avoid unnecessary, expensive, and sometimes painful treatments. Common skin conditions typically treated with topical preparations include skin diseases and allergies such as eczema, seborrhea, ringworm, and dermatitis. Topical preparations may also be used to treat psoriasis or other inflammatory skin diseases, such as dermatitis herpetiformis.

Anonymous Patient Answer

What is skin health?

Healthy skin aging begins to occur at a relatively young age. The onset of skin aging can be considered a marker of skin deterioration. Older skin may appear to age, while younger skin may appear youthful. Skin aging will continue throughout a person's lifespan, with visible changes in skin appearance occurring as a result of changes in collagen, the basic structural protein of the dermis. The skin and hair are constantly re-growing, but may be broken down and replaced over time by other substances. Aging skin and hair may present an unhealthy appearance, especially to individuals who are obese or suffer from other dermatological diseases such as sun exposure or hair thinning.

Anonymous Patient Answer

Can skin health be cured?

Patients were very much aware of skin health, especially regarding sun exposure. When skin health was considered in combination with other chronic diseases, the majority said both were possible to cure.

Anonymous Patient Answer

What causes skin health?

Skin health is highly variable, and can appear to be influenced by a variety of environmental and individual factors. It is essential for dermatologists to address common signs of skin health to enable them to identify which factors are contributing to the patient's underlying symptoms.

Anonymous Patient Answer

What does treatment usually treat?

Results from a recent paper indicate that treatment must include measures aimed at addressing the specific symptoms of the underlying disorders, including addressing the physical and cognitive symptoms of TCC.

Anonymous Patient Answer

What is the average age someone gets skin health?

The age of people has not changed significantly in almost two decades, and there is a lack of consensus among clinicians with regard to age at which it is prudent to begin treating people for skin diseases and conditions.

Anonymous Patient Answer

What is treatment?

Physicians' management of age-related skin conditions is highly dependent upon their level of knowledge and expertise. The key to the prevention of age-related skin conditions is in fostering earlier detection of these problems, which are then appropriately treated.

Anonymous Patient Answer

What is the latest research for skin health?

Most new research is aimed at the basic biology of skin. Basic research on skin health is more important than research aimed at developing practical, clinically proven treatments. There is no high-quality evidence of topical treatment effectiveness; topical treatments are often ineffective and can harm skin. Most research on cosmetics is based on observation. There is little information on the safety of cosmetics.

Anonymous Patient Answer

What are the common side effects of treatment?

The side effect profile of standard-of-care medications for psoriasis are similar to the profile described for biologics. This provides a basis for the continuation of the biologic therapies to other medications for moderate-to-severe psoriasis. You can find the most recent side effect profiles by using [Power] in both adults and children. This tool allows you to search trials tailored to your condition, location, and ideal treatment.

Anonymous Patient Answer

How does treatment work?

There is no standard treatment in skin allergy, and different skin diseases have different ways to resolve. However, skin disease can be treated in a number of different ways to achieve better results.

Anonymous Patient Answer
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