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Crystalloid Solution

Fluid Bolus (FB+) for Low Blood Pressure (HIPO Trial)

N/A
Waitlist Available
Led By James S Khan, MD
Research Sponsored by Mount Sinai Hospital, Canada
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 20 minutes after induction
Awards & highlights

HIPO Trial Summary

This trial is testing whether giving extra fluids before surgery can help reduce the risk of low blood pressure during anesthesia induction.

Eligible Conditions
  • Low Blood Pressure on Induction

HIPO Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~20 minutes after induction
This trial's timeline: 3 weeks for screening, Varies for treatment, and 20 minutes after induction for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Difference in the incidence of hypotension after induction of general anesthesia
Secondary outcome measures
Adverse events
The duration of post-induction hypotension
The incidence of surgical delays

HIPO Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Fluid Bolus (FB+)Active Control2 Interventions
Patients in the FB+ group will receive a single bolus of 500 ml of Ringer's Lactate over 5-10 minutes.
Group II: Non fluid bolus (FB-)Placebo Group1 Intervention
Patients in the FB- group will not receive a fluid bolus.

Find a Location

Who is running the clinical trial?

Mount Sinai Hospital, CanadaLead Sponsor
196 Previous Clinical Trials
67,568 Total Patients Enrolled
James S Khan, MDPrincipal InvestigatorMOUNT SINAI HOSPITAL

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this medical research extend to participants 85 years and older?

"The criteria for this medical research requires that all participants are between 18 and 70. Separate trials cater to minors under 18 years old, while those over 65 have their own 90-patient cohort."

Answered by AI

For whom is this clinical experiment open to participation?

"This medical trial seeks 40 patients aged 18 to 70 with hypotension who have a preoperative IVC-CI of 43% or higher on their POCUS scan. Additionally, these individuals should be undergoing elective surgery."

Answered by AI

Is this research currently taking on participants?

"This particular research endeavour, which was first made available on July 1st 2022 and last revised on June 30th of the same year, is not presently seeking participants. Nevertheless, there are still 110 other clinical trials accepting applications at this time."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
PoCUS Guided Fluids to Prevent Post-induction Hypotension
James Khan 2022. "PoCUS Guided Fluids to Prevent Post-induction Hypotension". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05424510.
~15 spots leftby Apr 2025
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