Intensive bimanual therapy for Cerebral Palsy

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Université Laval, Québec, Canada
Cerebral Palsy
Intensive bimanual therapy - Other
Eligibility
< 18
All Sexes
What conditions do you have?
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Study Summary

Motor disorders related to cerebral palsy are often accompanied by sensory, cognitive, perceptive, communication and behavioural impairments. It has already been shown that intensive bimanual intervention can improve arm movement, but its impact on the spontaneous use of the most affected arm in everyday life remains to be established. This project aims to understand the impacts of an intensive bimanual therapy on uni- and bi-manual motor functions as well as the spontaneous use of the most affected arm. Predictive value of neuroimaging variables will also be assessed.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

12 Primary · 2 Secondary · Reporting Duration: Measured 6-month post-intervention.

Measured 6-month post-intervention.
Clinical evaluation - Assisting Hand Assessment (AHA)
Clinical evaluation - Box and Blocks Test (BBT)
Clinical evaluation - Jebsen Taylor Test of Hand Function (JTTHF)
Clinical evaluation - Motor-Free Visual Perception Test-Revised (MVPT-R)
Clinical evaluation - Two-Arm Coordination Test (TACT)
Clinical evaluation -Two-point discrimination test (TPDT)
Robotic evaluation - Arm-position matching
Robotic evaluation - Ball on bar
Robotic evaluation - Object hit
Robotic evaluation - Visually guided reaching
Self-assessments - Canadian Occupational Performance Measure (COPM)
Self-assessments - Children's Hand-use Experience Questionnaire (CHEQ)
Day 6
Spontaneous use of both arms
Measured prior to the intervention.
Magnetic Resonance Imaging (MRI)

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

MANUS
1 of 1
Experimental Treatment

30 Total Participants · 1 Treatment Group

Primary Treatment: Intensive bimanual therapy · No Placebo Group · N/A

MANUS
Other
Experimental Group · 1 Intervention: Intensive bimanual therapy · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: measured 6-month post-intervention.
Closest Location: Université Laval · Québec, Canada
2005First Recorded Clinical Trial
1 TrialsResearching Cerebral Palsy
10 CompletedClinical Trials

Who is running the clinical trial?

Laval UniversityLead Sponsor
381 Previous Clinical Trials
154,156 Total Patients Enrolled
1 Trials studying Cerebral Palsy
16 Patients Enrolled for Cerebral Palsy

Eligibility Criteria

Age < 18 · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have a diagnosis of cerebral palsy or spastic hemiparesis encephalopathy.
You have a sensorimotor deficit of one or both upper limb.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.