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Physician Notification for Aortic Stenosis (DETECT AS Trial)

N/A

Recruiting

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Subjects with severe aortic stenosis having an aortic valve area of less than or equal to 1.0cm2.

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

DETECT AS Trial Summary

This trial is looking at whether electronic provider notification of severe aortic stenosis impacts its management, on the utilization of aortic valve replacement, and on ethnic and racial disparities in AVR utilization.

Who is the study for?

This trial is for patients with severe aortic stenosis, where the opening of their aortic valve is less than or equal to 1.0cm2. It's not for those who already have artificial (bioprosthetic or mechanical) valves in place.Check my eligibility

What is being tested?

The DETECT AS Trial tests if notifying physicians electronically about their patient's severe aortic stenosis improves management and increases the use of valve replacement surgery, especially among different ethnic and racial groups.See study design

What are the potential side effects?

Since this trial involves sending notifications rather than medical treatments, there are no direct side effects from interventions like drugs or surgeries.

DETECT AS Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My heart valve is severely narrowed.

DETECT AS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Establish impact of electronic physician notification letter on the likelihood of AVR utilization for patients with a clinical indication for severe AS

Secondary outcome measures

Impact on mortality rate

Impact on proportion of patients referred to Cardiology/Heart Valve Team

Impact on rate of heart failure hospitalization

+1 more

DETECT AS Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Notification Letter ArmExperimental Treatment1 Intervention

Providers that will receive an electronic Physician Notification Letter.

Group II: Control GroupActive Control1 Intervention

Providers that will not be contacted.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Edwards LifesciencesIndustry Sponsor

180 Previous Clinical Trials

60,634 Total Patients Enrolled

Massachusetts General HospitalLead Sponsor

2,933 Previous Clinical Trials

13,197,541 Total Patients Enrolled

Media Library

Physician Notification Letter Clinical Trial Eligibility Overview. Trial Name: NCT05230225 — N/A

Aortic Stenosis Research Study Groups: Notification Letter Arm, Control Group

Aortic Stenosis Clinical Trial 2023: Physician Notification Letter Highlights & Side Effects. Trial Name: NCT05230225 — N/A

Physician Notification Letter 2023 Treatment Timeline for Medical Study. Trial Name: NCT05230225 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there still capacity for enrolment in this experiment?

"Clinicaltrials.gov reports this medical trial is currently enrolling patients, with the initial posting of the study on February 9th 2022 and most recent update occuring April 4th 2022."

Answered by AI

What is the current participant headcount for this investigation?

"Affirmative. Clinicaltrials.gov's data indicates that this research project, which was initially announced on February 9th 2022, is presently enrolling participants. Altogether, the trial needs to recruit roughly 940 patients from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Electronic Physician Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: The DETECT AS Trial

Sammy Elmariah 2022. "Electronic Physician Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: The DETECT AS Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05230225.

All > Aortic Stenosis