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Electrical Stimulation

Electrical Stimulation + Resistance Training for Insulin Resistance Due to Obesity

Research Sponsored by University of Texas, El Paso
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights


This trial will study the effects of electrical stimulation and resistance training on insulin sensitivity in obese individuals.

Who is the study for?
This trial is for Mexican-Americans who are overweight or obese, have a sedentary lifestyle with less than 150 minutes of exercise per week, and do not use certain medications. Smokers, pregnant women, and those unwilling to follow the study plan cannot participate.Check my eligibility
What is being tested?
The study tests how well electrical stimulation combined with resistance training improves insulin sensitivity in participants. They'll be randomly assigned to one of four groups: control (sensory-level stimulation), NMES (visible muscle contraction), RT+NMES (stimulation during resistance training), or just resistance training.See study design
What are the potential side effects?
Possible side effects from the interventions may include discomfort at the stimulation site, muscle soreness similar to after exercising, skin irritation from electrodes or equipment used during sessions.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Glycemic Control
Secondary outcome measures
Amount of lean mass
Respiratory Exchange Ratio

Side effects data

From 2010 Phase 2 trial • 167 Patients • NCT00112151
Other noncardiovascular serious adverse events
Other nonserious adverse events
Persistently elevated PSA
Total serious cardiovascular adverse events
Persistently elevated HCT >= 54%
Elevated AUA
Study treatment Arm
Lower-range T
Higher-range T

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: Resistance Training + NMESExperimental Treatment2 Interventions
Participants will receive exercise training with stimulation up to maximum tolerable intensity.
Group II: NMESExperimental Treatment1 Intervention
Participants will receive stimulation up to maximum tolerable level.
Group III: ControlPlacebo Group1 Intervention
Participants will receive stimulation only up to sensory level.
Group IV: Resistance TrainingPlacebo Group2 Interventions
Participants will receive exercise training with stimulation up to sensory level.
First Studied
Drug Approval Stage
How many patients have taken this drug
Neuromuscular Electrical Stimulation

Find a Location

Who is running the clinical trial?

University of Texas, El PasoLead Sponsor
15 Previous Clinical Trials
3,063 Total Patients Enrolled

Media Library

Neuromuscular Electrical Stimulation (Electrical Stimulation) Clinical Trial Eligibility Overview. Trial Name: NCT03947697 — N/A
Obesity Research Study Groups: Resistance Training + NMES, Control, NMES, Resistance Training
Obesity Clinical Trial 2023: Neuromuscular Electrical Stimulation Highlights & Side Effects. Trial Name: NCT03947697 — N/A
Neuromuscular Electrical Stimulation (Electrical Stimulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03947697 — N/A
~8 spots leftby May 2025