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Motor Learning for Stroke Recovery

Phase < 1
Recruiting
Led By Kristan Leech, PT, DPT, PhD
Research Sponsored by University of Southern California
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Independently ambulatory (including the use of assistive devices)
Unilateral stroke
Timeline
Screening 3 weeks
Treatment Varies
Follow Up measured after motor learning in each testing session; participants will complete 2 testing sessions over approximately 1 months
Awards & highlights

Study Summary

This trial looks to improve walking in older adults post-stroke through a mix of biomechanical, neuropsychological, and brain imaging methods. It could lead to better treatment approaches to help those affected. #stroke

Who is the study for?
This trial is for older adults who had a stroke at least 6 months ago, can walk (with or without help), and have no severe cognitive deficits, dementia, uncontrolled high blood pressure, ongoing physical therapy for other conditions, or any metal implants that interfere with MRI scans.Check my eligibility
What is being tested?
The study aims to understand how cognitive impairments after a stroke affect the ability to learn new walking skills. It involves explicit and implicit motor learning tests combined with brain imaging and biomechanical analysis to see how these factors interact.See study design
What are the potential side effects?
There may be minimal side effects from participating in this trial as it mainly involves assessments and non-invasive brain imaging. However, some participants might experience fatigue during motor learning tasks or discomfort from being in an MRI machine.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can walk on my own, even if I need a device to help.
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I had a stroke that affected only one side of my body.
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I can walk for 5 minutes without needing to stop.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~measured after motor learning in each testing session; participants will complete 2 testing sessions over approximately 1 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and measured after motor learning in each testing session; participants will complete 2 testing sessions over approximately 1 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
step length asymmetry - change in performance
Secondary outcome measures
step length asymmetry - immediate retention

Trial Design

1Treatment groups
Experimental Treatment
Group I: Evaluating motor learning and brain structures post-strokeExperimental Treatment2 Interventions
We will use a single arm design to determine the impact of post-stroke cognitive impairment on two forms of motor learning (implicit and explicit) and evaluate the structural integrity of relevant brain structures in 65 individuals post stroke

Find a Location

Who is running the clinical trial?

University of Southern CaliforniaLead Sponsor
906 Previous Clinical Trials
1,596,111 Total Patients Enrolled
22 Trials studying Stroke
5,003 Patients Enrolled for Stroke
Kristan Leech, PT, DPT, PhDPrincipal InvestigatorUniversity of Southern California
1 Previous Clinical Trials
50 Total Patients Enrolled
1 Trials studying Stroke
50 Patients Enrolled for Stroke

Media Library

Explicit motor learning Clinical Trial Eligibility Overview. Trial Name: NCT04829071 — Phase < 1
Stroke Research Study Groups: Evaluating motor learning and brain structures post-stroke
Stroke Clinical Trial 2023: Explicit motor learning Highlights & Side Effects. Trial Name: NCT04829071 — Phase < 1
Explicit motor learning 2023 Treatment Timeline for Medical Study. Trial Name: NCT04829071 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the capacity for participants in this experiment?

"Correct. According to clinicaltrials.gov, this medical study was initially posted on January 16th 2023 and is still actively recruiting participants. The trial requires 65 patients from a single centre for completion."

Answered by AI

Are there any available openings for participants in this clinical experiment?

"Affirmative. Clinicaltrials.gov contains details that show this clinical study is actively looking for participants, which was originally posted on January 16th 2023 and recently updated on July 8th 2023. This trial requires 65 volunteers from a single medical site."

Answered by AI

Are there opportunities to join this research study?

"This experiment seeks 65 individuals, aged 45 to 85 years old, who experienced a stroke more than 6 months ago. Furthermore, applicants should possess unilateral paresis and be independently ambulatory (with or without the aid of assistive devices). They must also demonstrate their capability of walking for 5 minutes continuously in addition to answering no to all general health questions on the PAR-Q+. Lastly, participants need to agree with completing the set procedure throughout this trial."

Answered by AI

Does this research initiative include individuals aged 30 and over?

"The cut-off age for participants of this trial is 85 years old, with a minimum requirement of 45. Those younger than 18 or older that 65 are ineligible and can refer to 39 and 1056 trials respectively."

Answered by AI

Who else is applying?

What site did they apply to?
Center for Health Professions
What portion of applicants met pre-screening criteria?
Met criteria
~32 spots leftby Aug 2025