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Low Load Resistance Exercise + BFR for Mitochondria

N/A

Waitlist Available

Led By Brian Irving, PhD

Research Sponsored by Louisiana State University and A&M College

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up changes from baseline (pre-training) to follow-up (about 48-72 hours post-training)

Awards & highlights

Study Summary

This trial will study the effects of blood flow restricted (BFR) exercise on muscle adaptations in healthy young adults.

Eligible Conditions

Mitochondria
Muscle Strength
Enlargement

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ changes from baseline (pre-training) to follow-up (about 48-72 hours post-training)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~changes from baseline (pre-training) to follow-up (about 48-72 hours post-training)

This trial's timeline: 3 weeks for screening, Varies for treatment, and changes from baseline (pre-training) to follow-up (about 48-72 hours post-training) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in Mitochondrial Oxidative Capacity

Secondary outcome measures

Changes in Muscle Endurance measured using Isokinetic Dynamometry

Changes in Muscle Mass measured by Dual Energy X-ray Absorptiometry

Changes in Muscle Strength measured using Isokinetic Dynamometry

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Low Load Resistance Exercise + BFRExperimental Treatment1 Intervention

Subjects allocated to Low Load Resistance Exercise + BFR will undergo 6 weeks of single-legged low load (25%) resistance exercise plus blood flow restriction. Their contralateral leg will serve as within subject control.

Group II: Low Load Resistance ExerciseActive Control1 Intervention

Subjects allocated to Low Load Resistance Exercise will undergo 6 weeks of single-legged low load (25%) resistance exercise. Their contralateral leg will serve as within subject control.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Low Load Resistance Exercise + BFR

2019

N/A

~30

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Delfi, Inc.UNKNOWN

Louisiana State University and A&M CollegeLead Sponsor

9 Previous Clinical Trials

995 Total Patients Enrolled

Brian Irving, PhDPrincipal Investigator - Louisiana State University - Kinesiology

Louisiana State University and A&M College

1 Previous Clinical Trials

23 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this experiment still open for enrollment?

"Affirmative. The clinicaltrials.gov portal suggests that this trial is still looking to enrol patients, having first been posted on January 28th 2019 and lastly edited on August 1st 2022. It needs 30 volunteers from a single medical centre in order to be completed."

Answered by AI

What is the current cohort size of this research initiative?

"Affirmative. According to clinicaltrials.gov, the medical experiment was first advertised on January 28th 2019 and has recently been updated in August 1st 2022. Since then, 30 patients have been sought at a single research centre."

Answered by AI

Does this research trial have an age limit, and if so, does it preclude octogenarians?

"To qualify for inclusion in this trial, individuals must be aged between 18 and 40. Moreover, there are a total of 12 studies aimed at minors and 69 specifically geared towards the elderly population."

Answered by AI

Would I be able to join this clinical investigation?

"This trial is accepting 30 individuals aged 18 to 40 with hypertrophy and who are both capable of understanding the terms of inclusion as well as giving written informed consent."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

BFR and Muscle Mitochondrial Oxidative Capacity

Brian Irving 2019. "BFR and Muscle Mitochondrial Oxidative Capacity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03723226.