Exercise Training for Mental Illness
Trial Summary
What is the purpose of this trial?
The purpose of this research study is to examine the effect of various forms of exercise training on blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder (PTSD) and/or generalized anxiety disorder (GAD)).
Will I have to stop taking my current medications?
If you are taking medications that affect heart and blood vessel function, you may need to stop them to participate in this trial.
What data supports the effectiveness of the treatment Muscular Fitness Training Group, Strength Training, Resistance Training, Muscle Building Exercises, Muscular Strength Training Group, Resistance Training, Weight Training, Muscle Strengthening Exercise for mental illness?
Is resistance training safe for humans?
How does muscular fitness training differ from other treatments for mental illness?
Muscular fitness training, which includes strength and resistance exercises, is unique because it focuses on improving muscle strength and force-generating capacity, which can enhance functional performance and quality of life in patients with schizophrenia. Unlike other treatments that may target symptoms directly, this approach aims to restore physical capabilities and may indirectly improve mental health by increasing patient activation and overall well-being.368911
Research Team
Ryan Garten, PhD
Principal Investigator
Virginia Commonwealth University
Eligibility Criteria
This trial is for healthy individuals and those with PTSD or GAD who have specific scores on mental health scales. It's not for pregnant women, current/recent smokers, people with limited English proficiency, those on certain cardiovascular meds, drug/alcohol users, or anyone on a significant calorie restriction.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Initial Testing
Participants undergo initial testing to familiarize with study equipment and procedures, determine body measures, maximum strength, and require one blood draw
Testing Sessions
Participants undergo multiple tests to determine blood vessel health, including antioxidant or placebo administration
Exercise Training
Participants engage in 10 weeks of resistance training for muscular fitness or strength
Follow-up
Participants are monitored for changes in vascular function from baseline to the end of the final visit
Treatment Details
Interventions
- Muscular Fitness Training Group
- Muscular Strength Training Group
Find a Clinic Near You
Who Is Running the Clinical Trial?
Virginia Commonwealth University
Lead Sponsor