← Back to Search

Other

Brain Stimulation for Depression

N/A
Recruiting
Led By Ignacio Saez, Ph.D.
Research Sponsored by Icahn School of Medicine at Mount Sinai
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 1
Awards & highlights

Study Summary

This trial is studying electrical stimulation of the brain to treat depression in people with epilepsy.

Who is the study for?
This trial is for adults with major depressive disorder who are already undergoing invasive monitoring for epilepsy. It's open to all adult ages, except those over 80 due to cognitive decline concerns, and children under 18 because their frontal lobes aren't fully developed.Check my eligibility
What is being tested?
The study is testing new brain stimulation strategies targeting limbic brain areas involved in mood regulation and decision-making. Researchers will record neural activity during tasks that involve making choices to find potential treatment targets.See study design
What are the potential side effects?
Since this trial involves neurosurgical interventions and electrical stimulation of the brain, potential side effects may include discomfort at the electrode sites, headache, nausea, or other neurological effects.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 1
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Gambling Task
Secondary outcome measures
Beck's Depression I-II (BDI-II) score
Hamilton scales for depression and anxiety (HSDA)

Trial Design

1Treatment groups
Experimental Treatment
Group I: Participants with depressionExperimental Treatment1 Intervention
Participants with depression to undergo brain stimulation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Brain stimulation
2021
N/A
~80

Find a Location

Who is running the clinical trial?

National Institute of Mental Health (NIMH)NIH
2,785 Previous Clinical Trials
2,689,746 Total Patients Enrolled
667 Trials studying Depression
251,584 Patients Enrolled for Depression
Icahn School of Medicine at Mount SinaiLead Sponsor
860 Previous Clinical Trials
524,466 Total Patients Enrolled
35 Trials studying Depression
4,369 Patients Enrolled for Depression
University of California, DavisOTHER
911 Previous Clinical Trials
4,709,573 Total Patients Enrolled
12 Trials studying Depression
1,776 Patients Enrolled for Depression

Media Library

Brain stimulation (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05239780 — N/A
Depression Research Study Groups: Participants with depression
Depression Clinical Trial 2023: Brain stimulation Highlights & Side Effects. Trial Name: NCT05239780 — N/A
Brain stimulation (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05239780 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals are undergoing this clinical experiment?

"Affirmative. According to clinicaltrials.gov, this medical trial is actively recruiting individuals since its initial posting on October 6th 2021 and the most recent update of February 4th 2022. 10 subjects are needed from a single location for participation in the study."

Answered by AI

Is geriatric eligibility accepted for participation in this research?

"This medical trial has an age criteria of 18 to 80 years old for inclusion."

Answered by AI

Are researchers still recruiting participants for this experiment?

"Indeed, according to clinicaltrials.gov the trial is presently enrolling participants and has been accepting applications since October 6th 2021. The details of this study were last updated on February 4th 2022 and it calls for 10 individuals at a single location."

Answered by AI

Is there an eligibility criteria for participation in this clinical trial?

"To be eligible to participate in this research, prospective participants must have a major depressive disorder diagnosis and reside between the ages of 18 - 80. This trial is aiming to recruit 10 volunteers in total."

Answered by AI

Who else is applying?

What state do they live in?
South Dakota
How old are they?
18 - 65
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
What site did they apply to?
Icahn School of Medicine at Mount Sinai

Why did patients apply to this trial?

I’ve tried so many drugs and treatments for depression it won’t go away or if it does it just comes back.
PatientReceived 1 prior treatment
Recent research and studies
clinicaltrials.govStudy
Invasive Decoding and Stimulation of Altered Reward Computations in Depression
Ignacio Saez 2021. "Invasive Decoding and Stimulation of Altered Reward Computations in Depression". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05239780.
All > Depression New York
~6 spots leftby Aug 2027
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top