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Cognitive Behavioral Therapy for Adolescent Depression (PATHway Trial)
PATHway Trial Summary
This trial will test a "behavioral vaccine" to help prevent depression in adults. The vaccine will be tested in 4 health systems across the US.
PATHway Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPATHway Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.PATHway Trial Design
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Who is running the clinical trial?
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- My child's guardian has a cognitive or intellectual impairment.I have attempted suicide or self-harmed with moderate or greater severity.I am an adolescent who does not speak or read English.I am not interested in participating in the trial anymore.I am between 13 and 18 years old.I am currently in cognitive-behavioral therapy.I am currently on medication for depression, anxiety, or similar conditions.I am experiencing thoughts of harming myself.I have not had suicidal thoughts in the last 6 months.I am between the ages of 13 and 18.I am currently receiving treatment for a mood disorder.I am a teenager with mild to moderate depression.I have had depression in the past but am not currently experiencing it.I am not willing to follow the study rules.My parent or guardian does not speak English or Spanish.I am a teenager with mild to moderate depression.I am between 13 and 18 years old.
- Group 1: 1. No adolescent modules + no parent modules
- Group 2: 2. Adolescent behavioral activation modules only
- Group 3: 3. Adolescent cognitive-behavioral therapy modules only
- Group 4: 4. Adolescent interpersonal therapy modules only
- Group 5: 6. Adolescent behavioral activation modules + interpersonal therapy modules
- Group 6: 5. Adolescent behavioral activation modules + cognitive-behavioral therapy modules
- Group 7: 11. Adolescent cognitive-behavioral therapy modules + parent program modules
- Group 8: 16. All adolescent + parent program modules
- Group 9: 7. Adolescent cognitive-behavioral therapy modules + interpersonal therapy modules
- Group 10: 9. Parent program modules only
- Group 11: 10. Adolescent behavioral activation modules + parent program modules
- Group 12: 13. Adolescent behavioral activation + cognitive-behavioral therapy + parent program modules
- Group 13: 14. Adolescent behavioral activation + interpersonal therapy + parent program modules
- Group 14: 12. Adolescent interpersonal therapy modules + parent program modules
- Group 15: 15. Adolescent cognitive-behavioral therapy + interpersonal therapy + parent program modules
- Group 16: 8. Full Adolescent program only
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many healthcare facilities are participating in this research trial?
"At present, the trial is available at 6 distinct medical centres situated in Chicago, Glenview and Park Ridge among several other cities. For your convenience, we recommend that you choose a clinic close to your residence to reduce any unecessary travel needs associated with participation."
What sort of individuals does this clinical trial seek to recruit?
"In this trial, 400 adolescents aged 13 to 18 with a history of depressive episodes yet currently exhibiting elevated levels of depression (as indicated by PHQ-9 scores between 5 and 18) are desired."
Are new participants being recruited for this medical experiment?
"Affirmative. Clinicaltrials.gov verifies that this experiment, which was first publicized on December 1st 2021, is actively seeking volunteers. Approximately 400 individuals are needed for the 6 available sites."
How many recruits have been admitted to this experiment?
"Affirmative. Clinicaltrials.gov data reveals that the experiment, which was initially made accessible on December 1st 2021 is presently looking for participants in need of treatment. This trial requires 400 individuals to be sourced from 6 distinct sites."
Are seniors over 60 being admitted into this research program?
"This experiment is searching for individuals aged 13 to 18 years old."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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