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18F-DCFPyL PET/CT Imaging for Prostate Cancer

Phase 2 & 3

Waitlist Available

Research Sponsored by Sir Mortimer B. Davis - Jewish General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age 18 years or older

Able to tolerate the physical/logistical requirements of a PET/CT scan including lying supine (or prone) for up to 40 minutes and tolerating intravenous cannulation for injection

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 30 days

Awards & highlights

Study Summary

This trial is testing a new way to image prostate cancer in order to better understand how to treat it. Patients will receive an injection and then have a PET/CT scan. A panel of experts will review the images to see if they can better understand how to manage the disease.

Who is the study for?

Men over 18 with prostate cancer and signs of advanced disease, like bone pain or high PSA levels. They must be able to lie still for a PET/CT scan and fit within the machine's size limits. Those with severe claustrophobia, unstable health conditions, or who exceed the weight or size capacity for the PET/CT equipment cannot participate.Check my eligibility

What is being tested?

The trial is testing how well an imaging drug called 18F-DCFPyL works in detecting prostate cancer spread when used during a PET/CT scan. The goal is to see if this method changes doctors' decisions about patient care compared to standard methods.See study design

What are the potential side effects?

While not explicitly listed here, potential side effects may include reactions at the injection site, discomfort from lying still during scanning, and possible allergic reactions to the imaging agent.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 18 years old or older.

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I can lie still for 40 minutes and handle an IV injection for a PET/CT scan.

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My prostate cancer has returned, shown by rising PSA levels above 0.1 ng/ml.

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I am male.

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I have been diagnosed with prostate cancer and am under a doctor's care.

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I can care for myself but may not be able to do heavy physical work.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 30 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~30 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Differences in optimal clinical management

Secondary outcome measures

Adverse events

Scan positivity fraction in BCR by PSA.

Trial Design

1Treatment groups

Experimental Treatment

Group I: 18F-DCFPyL PET/CTExperimental Treatment1 Intervention

18F-DCFPyL PET/CT Scan

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

18F-DCFPyL PET/CT

2017

Completed Phase 2

~120

0 / 6Eligibility criteria met

Find a Location

Who is running the clinical trial?

Sir Mortimer B. Davis - Jewish General HospitalLead Sponsor

55 Previous Clinical Trials

19,660 Total Patients Enrolled

14 Trials studying Prostate Cancer

2,179 Patients Enrolled for Prostate Cancer

Media Library

Prostate Cancer Research Study Groups: 18F-DCFPyL PET/CT

Prostate Cancer Clinical Trial 2023: 18F-DCFPyL PET/CT Highlights & Side Effects. Trial Name: NCT03459820 — Phase 2 & 3

18F-DCFPyL PET/CT 2023 Treatment Timeline for Medical Study. Trial Name: NCT03459820 — Phase 2 & 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are we recruiting participants for this experiment at the moment?

"This clinical trial, as indicated on clinicaltrials.gov, is no longer recruiting patients. Although the study's last update was on May 3rd, 2022, it is not currently looking for any more participants. However, there are 1352 other clinical trials that are currently open for enrollment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Prostate Cancer Patient Management With 18F-DCFPyL PET/CT

Stephan Probst, MD 2018. "Prostate Cancer Patient Management With 18F-DCFPyL PET/CT". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03459820.

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