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Low Vt protocol for Congenital Heart Disease

N/A

Waitlist Available

Led By Phillip S Adams, DO

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up measurements will occur at the 5-minute equilibration period into the ventilation strategy.

Awards & highlights

Study Summary

This trial will investigate whether high or low tidal volume during cardiac catheterization impacts cardiac output.

Eligible Conditions

Congenital Heart Disease
Anesthesia

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ measurements will occur at the 5-minute equilibration period into the ventilation strategy.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~measurements will occur at the 5-minute equilibration period into the ventilation strategy.

This trial's timeline: 3 weeks for screening, Varies for treatment, and measurements will occur at the 5-minute equilibration period into the ventilation strategy. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Cardiac Output

Secondary outcome measures

Pulmonary arterial pressure

Pulmonary blood flow

Pulmonary vascular resistance

+2 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Low transition to High Vt protocolExperimental Treatment2 Interventions

This arm of the study will begin with lower tidal volumes at higher respiratory rates for initial hemodynamic measurements. They will then be transitioned to the higher tidal volume at lower respiratory rate condition for repeat hemodynamic measurement.

Group II: High transition to Low Vt protocolExperimental Treatment2 Interventions

This arm of the study will begin with higher tidal volumes at lower respiratory rates for initial hemodynamic measurements. They will then be transitioned to the lower tidal volume at higher respiratory rate condition for repeat hemodynamic measurement.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Low Vt protocol

2021

N/A

~40

High Vt protocol

2021

N/A

~40

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,722 Previous Clinical Trials

16,342,904 Total Patients Enrolled

Phillip S Adams, DOPrincipal InvestigatorUniversity of Pittsburgh

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants being sought for this clinical experiment at present?

"Affirmative. According to data found on the clinicaltrials.gov website, this study is actively enrolling participants and seeking 30 test subjects from a single location. The trial commenced on March 2nd 2021 and was last revised in October 10th 2022."

Answered by AI

How many participants can this research project accommodate?

"Yes, the information on clinicaltrials.gov confirms that this research is actively recruiting participants. It was initially posted on March 2nd 2021 and last revised on October 10th 2022 with a goal of enrolling 30 patients at one medical centre."

Answered by AI

Recent research and studies

CirculationJournal

Cardiopulmonary Interactions After Fontan Operations

Shekerdemian, Lara S., Andrew Bush, Darryl F. Shore, Christopher Lincoln, and Andrew N. Redington. 1997. “Cardiopulmonary Interactions After Fontan Operations”. Circulation. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/01.cir.96.11.3934.

clinicaltrials.govStudy

Fontan Physiology Ventilation Strategy

Phillip S. Adams, DO 2021. "Fontan Physiology Ventilation Strategy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04672538.