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On-Shift Napping for Endothelial Dysfunction

N/A

Waitlist Available

Led By P. Daniel Patterson

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 20-30 minutes for each arm/condition

Awards & highlights

Study Summary

This trial is testing whether it's feasible to collect blood pressure readings from night shift workers. They need 10 participants to consider it a success.

Who is the study for?

This study is for adults over 18 who work night shifts, especially in public safety or healthcare in Western Pennsylvania. They must be EMTs, paramedics, nurses, physicians, or similar professionals without a history of serious health conditions like heart disease or cancer.Check my eligibility

What is being tested?

The trial is testing the effects of taking brief naps during night shifts on cardiovascular health indicators such as blood pressure. It aims to see if enough data can be collected from participants during simulated night shift work.See study design

What are the potential side effects?

Since the intervention involves only brief on-shift napping and monitoring blood pressure, there are no direct side effects expected from this activity.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 20-30 minutes for each arm/condition

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~20-30 minutes for each arm/condition

This trial's timeline: 3 weeks for screening, Varies for treatment, and 20-30 minutes for each arm/condition for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of Participants for which at least 70% of required Ambulatory BP readings were collected

Secondary outcome measures

Average Reactive Hyperemia Index (RHI) after simulated night shift

Average Reactive Hyperemia Index (RHI) at baseline

Average blood pressure while awake during simulated night shift

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: The brief 45-minute nap, then no-napExperimental Treatment1 Intervention

Participants will be monitored for a total of 48 hours, including a 12-hour simulated night shift. At baseline (consent), participants are randomized to a crossover study design with two study arms (no nap, brief 45-minute nap). In this sequence, participants will perform the 12-hour simulated night shift with the brief 45-minute nap, undergo a 1-week minimum washout, then return to complete the 48-hour protocol again with the no-nap

Group II: No-nap, then brief 45-minute napExperimental Treatment1 Intervention

Participants will be monitored for a total of 48 hours, including a 12-hour simulated night shift. At baseline (consent), participants are randomized to a crossover study design with two study arms (no nap, brief 45-minute nap). In this sequence, participants will perform the 12-hour simulated night shift with no nap first, undergo a minimum of 1-week washout, then return complete the 48-hour protocol again with the brief 45-minute nap.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Brief on-shift nap

2022

N/A

~10

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,725 Previous Clinical Trials

16,305,791 Total Patients Enrolled

P. Daniel PattersonPrincipal InvestigatorUniversity of Pittsburgh

Media Library

Brief on-shift nap Clinical Trial Eligibility Overview. Trial Name: NCT05436951 — N/A

Endothelial Dysfunction Research Study Groups: The brief 45-minute nap, then no-nap, No-nap, then brief 45-minute nap

Endothelial Dysfunction Clinical Trial 2023: Brief on-shift nap Highlights & Side Effects. Trial Name: NCT05436951 — N/A

Brief on-shift nap 2023 Treatment Timeline for Medical Study. Trial Name: NCT05436951 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants able to join this experiment at the present time?

"Correct. The clinical trial listing on the website states that it is actively recruiting patients, with a starting date of June 28th and an update being made to the post on the same day. A total of 15 participants are sought from one centre for this research endeavour."

Answered by AI

How many individuals are being invited to participate in this experiment?

"Affirmative. Clinicaltrials.gov confirms that this medical experiment, first posted on June 28th 2022, is presently seeking volunteers. Around 15 people need to be acquired from 1 location for the trial's completion."

Answered by AI

What is the criteria to be eligible for this research program?

"This trial is seeking 15 participants aged 18-100 with endothelial dysfunction who are working adults. In particular, the study's investigators would like to recruit public safety and healthcare professionals in Western Pennsylvania that work night shifts as EMTs, paramedics, flight nurses/paramedics, firefighters or other types of clinicians such as nurses or physicians' assistants. Not having a license or certification does not automatically exclude someone from participation."

Answered by AI

Is eligibility for this trial restricted to those over twenty years of age?

"This clinical research accepts participants aged 18 to 100 years of age. For those underage and elderly, there are 9 trials for individuals below the age of majority and 111 studies dedicated to seniors respectively."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Night Shift Work, On-shift Napping, and Endothelial Function: A Pilot Study

Daniel Patterson, PhD, NRP 2022. "Night Shift Work, On-shift Napping, and Endothelial Function: A Pilot Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05436951.