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E-Cigarette Flavors and Nicotine Forms for Electronic Cigarettes Usage Effects

N/A

Recruiting

Led By Alison Breland, PhD

Research Sponsored by Virginia Commonwealth University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline (approx 90 min after session start) to after final product usage (up to 185 min)

Awards & highlights

Study Summary

This trial studies how different e-cig nicotine types, sweetness and forms affect blood nicotine, use & feelings.

Who is the study for?

This trial is for healthy adults aged 18-65 who currently use cigarettes, e-cigarettes, or both. Participants must be willing to give informed consent, able to attend lab sessions and abstain from tobacco/nicotine when needed, and follow the study's product usage guidelines.Check my eligibility

What is being tested?

The study is testing how different e-cigarette liquids with varying levels of sweetness and nicotine forms affect blood nicotine concentration, puffing behavior, and subjective experiences.See study design

What are the potential side effects?

While not explicitly stated in the provided information, potential side effects may include throat irritation, coughing, dry mouth or throat due to vaping; specific side effects will depend on individual reactions to the e-liquid components.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline (approx 90 min after session start) to after final product usage (up to 165 min)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline (approx 90 min after session start) to after final product usage (up to 165 min)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (approx 90 min after session start) to after final product usage (up to 165 min) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Challenge paradigm latency

Challenge paradigm puffs

Body Weight Changes

+2 more

Other outcome measures

Change in Direct Effects of Product use Questionnaires

Change in General Labeled Magnitude Scale

Change in Hughes-Hatsukami Questionnaire

+1 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Cigarette and/or e-Cigarette usersExperimental Treatment4 Interventions

Each participant will participate in 4 sessions. During each session, participants will first complete a 10-puff product use period with the ECIG assigned for that session, then a 30-minute ad lib product use period, and then a cigarette/e-cigarette challenge paradigm.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Virginia Commonwealth UniversityLead Sponsor

699 Previous Clinical Trials

22,885,013 Total Patients Enrolled

4 Trials studying Electronic Cigarettes

137 Patients Enrolled for Electronic Cigarettes

National Institute on Drug Abuse (NIDA)NIH

2,470 Previous Clinical Trials

2,619,699 Total Patients Enrolled

4 Trials studying Electronic Cigarettes

195 Patients Enrolled for Electronic Cigarettes

Alison Breland, PhDPrincipal InvestigatorVirginia Commonwealth University

9 Previous Clinical Trials

445 Total Patients Enrolled

3 Trials studying Electronic Cigarettes

89 Patients Enrolled for Electronic Cigarettes

Media Library

Cigarette and/or e-Cigarette users Clinical Trial Eligibility Overview. Trial Name: NCT05587504 — N/A

Electronic Cigarettes Research Study Groups: Cigarette and/or e-Cigarette users

Electronic Cigarettes Clinical Trial 2023: Cigarette and/or e-Cigarette users Highlights & Side Effects. Trial Name: NCT05587504 — N/A

Cigarette and/or e-Cigarette users 2023 Treatment Timeline for Medical Study. Trial Name: NCT05587504 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research open to participants below the age of seventy?

"In accordance with the trial's inclusion criteria, individuals over 18 and under 65 years of age may be eligible to participate."

Answered by AI

Are there any remaining openings for participants in this experiment?

"Clinicaltrials.gov reveals that this clinical trial, which first appeared on December 1st 2022, is no longer open to applicants. Fortunately, there are still other trials seeking participants at the present moment."

Answered by AI

How could I potentially participate in this clinical research?

"Eligibility criteria for this medical trial necessitates that participants possess electronic cigarettes and fall in the age range of 18 to 65. 32 individuals are currently being sought out by researchers."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Determination of Liquid Flavor and Nicotine Form Outcomes

2023. "Determination of Liquid Flavor and Nicotine Form Outcomes". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05587504.